Abstract
(/sup 18/F)Fluoride was produced via the /sup 18/O (p,n) /sup 18/F reaction using a low volume stainless steel /sup 18/O-water target in a small cyclotron. The average /sup 18/F production rate for 60 runs was about 720 ..mu..Ci/..mu..A-min. A typical bombardment time of 20 min produced 120 mCi of /sup 18/F-fluoride. (/sup 18/F)2-fluoro-2-deoxy-D-glucose ((/sup 18/F)2FDG) was prepared using the procedure developed by Tewson (J. Nucl. Med. 24, 718 (1983)) involving a protected cyclic sulfate glucose derivative as precursor. The routine synthesis and quality testing of (/sup 18/F)2FDG required 1 h and, typically, yields of 30-35 mCi of >95% HPLC-pure product were obtained.
Citation Formats
Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, and Cooper, M D.
(/sup 18/F)fluoride from a small cyclotron for the routine synthesis of (/sup 18/F)2-fluoro-2-deoxy-D-glucose.
United Kingdom: N. p.,
1986.
Web.
doi:10.1016/0883-2889(86)90095-X.
Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, & Cooper, M D.
(/sup 18/F)fluoride from a small cyclotron for the routine synthesis of (/sup 18/F)2-fluoro-2-deoxy-D-glucose.
United Kingdom.
https://doi.org/10.1016/0883-2889(86)90095-X
Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, and Cooper, M D.
1986.
"(/sup 18/F)fluoride from a small cyclotron for the routine synthesis of (/sup 18/F)2-fluoro-2-deoxy-D-glucose."
United Kingdom.
https://doi.org/10.1016/0883-2889(86)90095-X.
@misc{etde_5734944,
title = {(/sup 18/F)fluoride from a small cyclotron for the routine synthesis of (/sup 18/F)2-fluoro-2-deoxy-D-glucose}
author = {Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, and Cooper, M D}
abstractNote = {(/sup 18/F)Fluoride was produced via the /sup 18/O (p,n) /sup 18/F reaction using a low volume stainless steel /sup 18/O-water target in a small cyclotron. The average /sup 18/F production rate for 60 runs was about 720 ..mu..Ci/..mu..A-min. A typical bombardment time of 20 min produced 120 mCi of /sup 18/F-fluoride. (/sup 18/F)2-fluoro-2-deoxy-D-glucose ((/sup 18/F)2FDG) was prepared using the procedure developed by Tewson (J. Nucl. Med. 24, 718 (1983)) involving a protected cyclic sulfate glucose derivative as precursor. The routine synthesis and quality testing of (/sup 18/F)2FDG required 1 h and, typically, yields of 30-35 mCi of >95% HPLC-pure product were obtained.}
doi = {10.1016/0883-2889(86)90095-X}
journal = []
volume = {37:5}
journal type = {AC}
place = {United Kingdom}
year = {1986}
month = {Jan}
}
title = {(/sup 18/F)fluoride from a small cyclotron for the routine synthesis of (/sup 18/F)2-fluoro-2-deoxy-D-glucose}
author = {Dejesus, O T, Martin, J A, Yasillo, N J, Gatley, S J, and Cooper, M D}
abstractNote = {(/sup 18/F)Fluoride was produced via the /sup 18/O (p,n) /sup 18/F reaction using a low volume stainless steel /sup 18/O-water target in a small cyclotron. The average /sup 18/F production rate for 60 runs was about 720 ..mu..Ci/..mu..A-min. A typical bombardment time of 20 min produced 120 mCi of /sup 18/F-fluoride. (/sup 18/F)2-fluoro-2-deoxy-D-glucose ((/sup 18/F)2FDG) was prepared using the procedure developed by Tewson (J. Nucl. Med. 24, 718 (1983)) involving a protected cyclic sulfate glucose derivative as precursor. The routine synthesis and quality testing of (/sup 18/F)2FDG required 1 h and, typically, yields of 30-35 mCi of >95% HPLC-pure product were obtained.}
doi = {10.1016/0883-2889(86)90095-X}
journal = []
volume = {37:5}
journal type = {AC}
place = {United Kingdom}
year = {1986}
month = {Jan}
}