Abstract
A solid-phase radioimmunoassay for quantitating anti-double-stranded deoxyribonucleic acid antibodies (anti-dsDNA) in IgG, IgM and IgA classes has been devised. A distinct feature of the method is an application of polystyrene tubes coated with poly-L-lysine, through which dsDNA could be bound firmly to a solid phase. Studies on patients sera as well as normal sera revealed that anti-dsDNA was not qualitatively but quantitatively characteristic of systematic lupus erythematosus (SLE) and that IgG anti-dsDNA levels correlated well with the disease activity.
Aotsuka, S;
Okawa, M;
Ikebe, K;
Yokohari, R
[1]
- Division of Clinical Immunology, Clinical Research Institute, National Medical Center Hospital, Shinjuku-ku, Tokyo, Japan
Citation Formats
Aotsuka, S, Okawa, M, Ikebe, K, and Yokohari, R.
Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes.
Netherlands: N. p.,
1979.
Web.
Aotsuka, S, Okawa, M, Ikebe, K, & Yokohari, R.
Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes.
Netherlands.
Aotsuka, S, Okawa, M, Ikebe, K, and Yokohari, R.
1979.
"Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes."
Netherlands.
@misc{etde_5733965,
title = {Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes}
author = {Aotsuka, S, Okawa, M, Ikebe, K, and Yokohari, R}
abstractNote = {A solid-phase radioimmunoassay for quantitating anti-double-stranded deoxyribonucleic acid antibodies (anti-dsDNA) in IgG, IgM and IgA classes has been devised. A distinct feature of the method is an application of polystyrene tubes coated with poly-L-lysine, through which dsDNA could be bound firmly to a solid phase. Studies on patients sera as well as normal sera revealed that anti-dsDNA was not qualitatively but quantitatively characteristic of systematic lupus erythematosus (SLE) and that IgG anti-dsDNA levels correlated well with the disease activity.}
journal = []
volume = {28:1-2}
journal type = {AC}
place = {Netherlands}
year = {1979}
month = {Jul}
}
title = {Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes}
author = {Aotsuka, S, Okawa, M, Ikebe, K, and Yokohari, R}
abstractNote = {A solid-phase radioimmunoassay for quantitating anti-double-stranded deoxyribonucleic acid antibodies (anti-dsDNA) in IgG, IgM and IgA classes has been devised. A distinct feature of the method is an application of polystyrene tubes coated with poly-L-lysine, through which dsDNA could be bound firmly to a solid phase. Studies on patients sera as well as normal sera revealed that anti-dsDNA was not qualitatively but quantitatively characteristic of systematic lupus erythematosus (SLE) and that IgG anti-dsDNA levels correlated well with the disease activity.}
journal = []
volume = {28:1-2}
journal type = {AC}
place = {Netherlands}
year = {1979}
month = {Jul}
}