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Case immunologically disturbed by thorotrast-induced hepatoma

Abstract

A case, 57 years old man, with thorotrast-induced hepatocellular carcinoma was reported. Thorium deposits in the reticuloendothelial tissues have the hazardous radiation effects on those tissues forever. In this case, the mean thorium amount in the spleen was 28.4% and the mean activity ratio of Ac-228 to Th-232 was 0.948. These values were much different from those reported by Kato in 1968. The ratio of T-cell to T.B. population decreased and PPD and PHA intradermal skin test were negative. Plasma cells in bone marrow increased and IgG was 4 g/dl. In these immunological studies it was supposed that T-cell function was impaired and B-cell function, especially IgG fraction was stimulated.
Authors:
Boku, S; Kato, M; Okuyama, T; Masuzawa, Manabu; Matsuo, S [1] 
  1. National Osaka Hospital (Japan)
Publication Date:
Oct 01, 1980
Product Type:
Journal Article
Reference Number:
AIX-12-624776; ERA-07-023412; EDB-82-051173
Resource Relation:
Journal Name: Kanzo; (Japan); Journal Volume: 21:10
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; THOROTRAST; DELAYED RADIATION EFFECTS; BLOOD COUNT; HEPATOMAS; IMMUNITY; LIVER; LYMPHOCYTES; PATIENTS; RADIOACTIVITY; ACTINIDE COMPOUNDS; ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CHALCOGENIDES; COLLOIDS; CONNECTIVE TISSUE CELLS; CONTRAST MEDIA; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; GLANDS; LEUKOCYTES; MATERIALS; NEOPLASMS; ORGANS; OXIDES; OXYGEN COMPOUNDS; RADIATION EFFECTS; RADIOCOLLOIDS; SOMATIC CELLS; THORIUM COMPOUNDS; THORIUM OXIDES; 560161* - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5725785
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KNZOA
Submitting Site:
INIS
Size:
Pages: 1379-1389
Announcement Date:
Sep 01, 1981

Citation Formats

Boku, S, Kato, M, Okuyama, T, Masuzawa, Manabu, and Matsuo, S. Case immunologically disturbed by thorotrast-induced hepatoma. Japan: N. p., 1980. Web.
Boku, S, Kato, M, Okuyama, T, Masuzawa, Manabu, & Matsuo, S. Case immunologically disturbed by thorotrast-induced hepatoma. Japan.
Boku, S, Kato, M, Okuyama, T, Masuzawa, Manabu, and Matsuo, S. 1980. "Case immunologically disturbed by thorotrast-induced hepatoma." Japan.
@misc{etde_5725785,
title = {Case immunologically disturbed by thorotrast-induced hepatoma}
author = {Boku, S, Kato, M, Okuyama, T, Masuzawa, Manabu, and Matsuo, S}
abstractNote = {A case, 57 years old man, with thorotrast-induced hepatocellular carcinoma was reported. Thorium deposits in the reticuloendothelial tissues have the hazardous radiation effects on those tissues forever. In this case, the mean thorium amount in the spleen was 28.4% and the mean activity ratio of Ac-228 to Th-232 was 0.948. These values were much different from those reported by Kato in 1968. The ratio of T-cell to T.B. population decreased and PPD and PHA intradermal skin test were negative. Plasma cells in bone marrow increased and IgG was 4 g/dl. In these immunological studies it was supposed that T-cell function was impaired and B-cell function, especially IgG fraction was stimulated.}
journal = []
volume = {21:10}
journal type = {AC}
place = {Japan}
year = {1980}
month = {Oct}
}