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Recovery from UV-induced potentially lethal damage in systemic lupus erythematosus skin fibroblasts

Abstract

The repair of ultraviolet light-induced potentially lethal damage was investigated in density-inhibited skin fibroblast cell strains derived from patients with systemic lupus erythematosus. The effect of exposure to polychromatic ultraviolet light composed of environmentally relevant wavelengths or to the more commonly studied, short wavelength (254 nm) ultraviolet light was studied. Systemic lupus erythematosus cells, which are hypersensitive to ultraviolet light under growth promoting conditions, were able to repair potentially lethal damage as well as normal cells.
Authors:
Publication Date:
Aug 01, 1986
Product Type:
Journal Article
Reference Number:
GBN-86-004027; EDB-88-021417
Resource Relation:
Journal Name: Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.; (United Kingdom); Journal Volume: 50:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; LUPUS; NEAR ULTRAVIOLET RADIATION; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; CELL CYCLE; FIBROBLASTS; GROWTH; LETHAL IRRADIATION; RESPONSE MODIFYING FACTORS; SKIN; SURVIVAL CURVES; ANIMAL CELLS; BACTERIAL DISEASES; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BODY; CONNECTIVE TISSUE CELLS; DISEASES; ELECTROMAGNETIC RADIATION; INFECTIOUS DISEASES; IRRADIATION; ORGANS; RADIATION EFFECTS; RADIATIONS; RECOVERY; REPAIR; SKIN DISEASES; SOMATIC CELLS; TUBERCULOSIS; ULTRAVIOLET RADIATION; 560120* - Radiation Effects on Biochemicals, Cells, & Tissue Culture
OSTI ID:
5717878
Research Organizations:
Boston Univ., MA, USA. School of Medicine
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IJRBA
Submitting Site:
GBN
Size:
Pages: 305-312
Announcement Date:
Dec 01, 1987

Citation Formats

Zamansky, G B. Recovery from UV-induced potentially lethal damage in systemic lupus erythematosus skin fibroblasts. United Kingdom: N. p., 1986. Web.
Zamansky, G B. Recovery from UV-induced potentially lethal damage in systemic lupus erythematosus skin fibroblasts. United Kingdom.
Zamansky, G B. 1986. "Recovery from UV-induced potentially lethal damage in systemic lupus erythematosus skin fibroblasts." United Kingdom.
@misc{etde_5717878,
title = {Recovery from UV-induced potentially lethal damage in systemic lupus erythematosus skin fibroblasts}
author = {Zamansky, G B}
abstractNote = {The repair of ultraviolet light-induced potentially lethal damage was investigated in density-inhibited skin fibroblast cell strains derived from patients with systemic lupus erythematosus. The effect of exposure to polychromatic ultraviolet light composed of environmentally relevant wavelengths or to the more commonly studied, short wavelength (254 nm) ultraviolet light was studied. Systemic lupus erythematosus cells, which are hypersensitive to ultraviolet light under growth promoting conditions, were able to repair potentially lethal damage as well as normal cells.}
journal = []
volume = {50:2}
journal type = {AC}
place = {United Kingdom}
year = {1986}
month = {Aug}
}