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The inactivation of hepatitis A virus and other model viruses by UV irradiation

Abstract

Ultraviolet light is an attractive alternative to chemical disinfection of water, but little is known about its ability to inactivate important waterborne pathogens such as hepatitis A virus. Therefore, the sensitivity of HAV strain HM-175, coxsackievirus type B-5, rotavirus strain SA-11, and bacteriophages MS2 and [phi]X174 to ultraviolet radiation of 254 nm wavelength in phosphate buffered water was determined. Purified stocks of the viruses were combined and exposed to collimated UV radiation in a stirred reactor for a total dose of up to 40 mW sec/cm[sup 2]. Virus survival kinetics were determined from samples removed at dose intervals. The results of these experiments indicate that UV radiation can effectively inactivate viruses of public health concern in drinking water. (author).
Authors:
Battigelli, D A; Sobsey, M D; Lobe, D C [1] 
  1. North Carolina Univ., Chapel Hill, NC (United States). Dept. of Environmental Sciences
Publication Date:
Jan 01, 1993
Product Type:
Conference
Report Number:
CONF-9205117-
Reference Number:
AIX-25-005858; EDB-94-021611
Resource Relation:
Journal Name: Water Science and Technology; (United Kingdom); Journal Volume: 27:3-4; Conference: 16. biennial conference of the International Association on Water Pollution Research and Control: water quality international, Washington, DC (United States), 24-30 May 1992
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BACTERIOPHAGES; BIOLOGICAL RADIATION EFFECTS; HEPATITIS; STERILIZATION; DRINKING WATER; ULTRAVIOLET RADIATION; IRRADIATION; RADIATION DOSES; SURVIVAL CURVES; WATER QUALITY; BIOLOGICAL EFFECTS; DIGESTIVE SYSTEM DISEASES; DISEASES; DOSES; ELECTROMAGNETIC RADIATION; ENVIRONMENTAL QUALITY; HYDROGEN COMPOUNDS; MICROORGANISMS; OXYGEN COMPOUNDS; PARASITES; RADIATION EFFECTS; RADIATIONS; VIRUSES; WATER; 560120* - Radiation Effects on Biochemicals, Cells, & Tissue Culture
OSTI ID:
5709110
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0273-1223; CODEN: WSTED4
Submitting Site:
GBN
Size:
Pages: 339-342
Announcement Date:
May 13, 2001

Citation Formats

Battigelli, D A, Sobsey, M D, and Lobe, D C. The inactivation of hepatitis A virus and other model viruses by UV irradiation. United Kingdom: N. p., 1993. Web.
Battigelli, D A, Sobsey, M D, & Lobe, D C. The inactivation of hepatitis A virus and other model viruses by UV irradiation. United Kingdom.
Battigelli, D A, Sobsey, M D, and Lobe, D C. 1993. "The inactivation of hepatitis A virus and other model viruses by UV irradiation." United Kingdom.
@misc{etde_5709110,
title = {The inactivation of hepatitis A virus and other model viruses by UV irradiation}
author = {Battigelli, D A, Sobsey, M D, and Lobe, D C}
abstractNote = {Ultraviolet light is an attractive alternative to chemical disinfection of water, but little is known about its ability to inactivate important waterborne pathogens such as hepatitis A virus. Therefore, the sensitivity of HAV strain HM-175, coxsackievirus type B-5, rotavirus strain SA-11, and bacteriophages MS2 and [phi]X174 to ultraviolet radiation of 254 nm wavelength in phosphate buffered water was determined. Purified stocks of the viruses were combined and exposed to collimated UV radiation in a stirred reactor for a total dose of up to 40 mW sec/cm[sup 2]. Virus survival kinetics were determined from samples removed at dose intervals. The results of these experiments indicate that UV radiation can effectively inactivate viruses of public health concern in drinking water. (author).}
journal = []
volume = {27:3-4}
place = {United Kingdom}
year = {1993}
month = {Jan}
}