You need JavaScript to view this

Cytological studies of esophageal carcinoma and gastric carcinoma receiving radiation and chemotherapy

Journal Article:

Abstract

The cytology of the endoscopic biopsy materials from 85 cases of esophageal cancer were analyzed for effects of the combined radiotherapy with Bleomycin. Cancer cells were remarkably decreased in number after the combination therapy. Unaffected cancer cells declined to negligible levels in 64 of 79 esophageal cancer cases irradiated more than 6,000 rad. Out of 42 gastric cancer cases treated with only anticancer drugs, 37 cases exhibited cytologic changes in the smears of biopsied materials. About the remnant 5 cases, cancer cells showed partially cytoplasmic swelling, nuclear enlargement and nuclear abnormal stain. The smears of the biopsy and resected specimens from 64 gastric cancer cases with radiation and chemotherapy were cytologically discussed. The combination therapy increased the amount of both necrotic materials and neutrophils in the smears. The cytoplasms of treated cancer cells were swollen, vacuolated and stained abnormally. The nuclei of cancer cells became enlarged, multiple, piknotic and/or stained pale. Nuclear swelling was more prominent in cancer cells of differentiated adenocarcinomas. Cancer cells were decreased in number almost in inverse proportion to irradiation dose. Unaffected cancer cells were disappeared in 13 of 24 cases irradiated more than 6,000 rad, in 7 of 35 cases irradiated in the range 3,000  More>>
Authors:
Takeda, T; Nakano, N; Asakawa, H [1] 
  1. Miyagi Prefectural Adult Disease Center, Natori (Japan)
Publication Date:
Oct 01, 1982
Product Type:
Journal Article
Reference Number:
AIX-14-779596; EDB-83-179908
Resource Relation:
Journal Name: Gan to Kagaku Ryoho; (Japan); Journal Volume: 9:10
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CARCINOMAS; RADIOTHERAPY; ESOPHAGUS; STOMACH; BIOLOGICAL RADIATION EFFECTS; BIOPSY; BLEOMYCIN; CHEMOTHERAPY; CYTOLOGY; DOSE-RESPONSE RELATIONSHIPS; PATIENTS; ANTI-INFECTIVE AGENTS; ANTIBIOTICS; ANTIMITOTIC DRUGS; ANTINEOPLASTIC DRUGS; BIOLOGICAL EFFECTS; BIOLOGY; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; DRUGS; GASTROINTESTINAL TRACT; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIOLOGY; THERAPY; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
5699059
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: GTKRD
Submitting Site:
HEDB
Size:
Pages: 1711-1715
Announcement Date:
Aug 01, 1983

Journal Article:

Citation Formats

Takeda, T, Nakano, N, and Asakawa, H. Cytological studies of esophageal carcinoma and gastric carcinoma receiving radiation and chemotherapy. Japan: N. p., 1982. Web.
Takeda, T, Nakano, N, & Asakawa, H. Cytological studies of esophageal carcinoma and gastric carcinoma receiving radiation and chemotherapy. Japan.
Takeda, T, Nakano, N, and Asakawa, H. 1982. "Cytological studies of esophageal carcinoma and gastric carcinoma receiving radiation and chemotherapy." Japan.
@misc{etde_5699059,
title = {Cytological studies of esophageal carcinoma and gastric carcinoma receiving radiation and chemotherapy}
author = {Takeda, T, Nakano, N, and Asakawa, H}
abstractNote = {The cytology of the endoscopic biopsy materials from 85 cases of esophageal cancer were analyzed for effects of the combined radiotherapy with Bleomycin. Cancer cells were remarkably decreased in number after the combination therapy. Unaffected cancer cells declined to negligible levels in 64 of 79 esophageal cancer cases irradiated more than 6,000 rad. Out of 42 gastric cancer cases treated with only anticancer drugs, 37 cases exhibited cytologic changes in the smears of biopsied materials. About the remnant 5 cases, cancer cells showed partially cytoplasmic swelling, nuclear enlargement and nuclear abnormal stain. The smears of the biopsy and resected specimens from 64 gastric cancer cases with radiation and chemotherapy were cytologically discussed. The combination therapy increased the amount of both necrotic materials and neutrophils in the smears. The cytoplasms of treated cancer cells were swollen, vacuolated and stained abnormally. The nuclei of cancer cells became enlarged, multiple, piknotic and/or stained pale. Nuclear swelling was more prominent in cancer cells of differentiated adenocarcinomas. Cancer cells were decreased in number almost in inverse proportion to irradiation dose. Unaffected cancer cells were disappeared in 13 of 24 cases irradiated more than 6,000 rad, in 7 of 35 cases irradiated in the range 3,000 to 6,000 rad, in none of 5 cases irradiated less than 3,000 rad.}
journal = {Gan to Kagaku Ryoho; (Japan)}
volume = {9:10}
journal type = {AC}
place = {Japan}
year = {1982}
month = {Oct}
}