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Radioimmunoassay in the diagnosis of arterial hypertension

Abstract

The paper is concerned with the results of a study of the aldosterone concentration and renin activity, the general level of catecholamines and their fractions in the peripheral blood and blood taken at selective venography from the vena cava inferior, renal and adrenal veins of 108 patients with hypertension, aldosteroma and idiopathic hyperaldosteronism, adrenal and extraadrenal pheochromocytoma, renovascular and renoparenchymatous arterial hypertension. The aldosterone concentration and renin activity were determined with radioimmunoassay, and the general content of catecholamines and their fractions with a radioenzymatic method using standard kits. It has been shown that the radioimmunoassay to determine the aldosterone concentration and renin activity makes possible differential diagnosis of hypertension, aldosteroma, idiopathic and secondary hyperaldosteronism. A considerable increase in the blood plasma renin activity on the affected side was revealed in the patients with renovascular hypertension, and in renoparenchymatous hypertension it was equal in both renal veins. The study of the total content of catecholamines and their fractions in the blood from different parts of the venous system can be used for topical diagnosis of adrenal and extraadrenal pheochromocytoma.
Authors:
Slavnov, V N; Olejnik, V A; Yakovlev, A A; Yugrinov, O G; Markov, V V [1] 
  1. Kievskij Nauchno-Issledovatel'skij Inst. Ehndokrinologii i Obmena Veshchestv (Ukrainian SSR)
Publication Date:
Nov 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-050335; EDB-85-116279
Resource Relation:
Journal Name: Med. Radiol.; (USSR); Journal Volume: 29:11
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALDOSTERONE; RADIOIMMUNOASSAY; HYPERTENSION; DIAGNOSIS; RENIN; ADRENAL GLANDS; BIOLOGICAL FUNCTIONS; BIOMEDICAL RADIOGRAPHY; BLOOD PLASMA; CATALYSIS; CATECHOLAMINES; KIDNEYS; METABOLISM; NEOPLASMS; PATIENTS; URINE; UROGENITAL SYSTEM DISEASES; VASCULAR DISEASES; VEINS; ADRENAL HORMONES; ALDEHYDES; AMINES; AROMATICS; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BLOOD; BLOOD VESSELS; BODY; BODY FLUIDS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; CORTICOSTEROIDS; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE GLANDS; ENZYMES; FUNCTIONS; GLANDS; HORMONES; HYDROLASES; HYDROXY COMPOUNDS; ISOTOPE APPLICATIONS; KETONES; MATERIALS; MEDICINE; MINERALOCORTICOIDS; NONSPECIFIC PEPTIDASES; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HYDROLASES; PHENOLS; POLYPHENOLS; PREGNANES; RADIOASSAY; RADIOLOGY; STEROID HORMONES; STEROIDS; SYMPTOMS; TRACER TECHNIQUES; WASTES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5679415
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: MERAA
Submitting Site:
HEDB
Size:
Pages: 15-19
Announcement Date:
Jul 01, 1985

Citation Formats

Slavnov, V N, Olejnik, V A, Yakovlev, A A, Yugrinov, O G, and Markov, V V. Radioimmunoassay in the diagnosis of arterial hypertension. USSR: N. p., 1984. Web.
Slavnov, V N, Olejnik, V A, Yakovlev, A A, Yugrinov, O G, & Markov, V V. Radioimmunoassay in the diagnosis of arterial hypertension. USSR.
Slavnov, V N, Olejnik, V A, Yakovlev, A A, Yugrinov, O G, and Markov, V V. 1984. "Radioimmunoassay in the diagnosis of arterial hypertension." USSR.
@misc{etde_5679415,
title = {Radioimmunoassay in the diagnosis of arterial hypertension}
author = {Slavnov, V N, Olejnik, V A, Yakovlev, A A, Yugrinov, O G, and Markov, V V}
abstractNote = {The paper is concerned with the results of a study of the aldosterone concentration and renin activity, the general level of catecholamines and their fractions in the peripheral blood and blood taken at selective venography from the vena cava inferior, renal and adrenal veins of 108 patients with hypertension, aldosteroma and idiopathic hyperaldosteronism, adrenal and extraadrenal pheochromocytoma, renovascular and renoparenchymatous arterial hypertension. The aldosterone concentration and renin activity were determined with radioimmunoassay, and the general content of catecholamines and their fractions with a radioenzymatic method using standard kits. It has been shown that the radioimmunoassay to determine the aldosterone concentration and renin activity makes possible differential diagnosis of hypertension, aldosteroma, idiopathic and secondary hyperaldosteronism. A considerable increase in the blood plasma renin activity on the affected side was revealed in the patients with renovascular hypertension, and in renoparenchymatous hypertension it was equal in both renal veins. The study of the total content of catecholamines and their fractions in the blood from different parts of the venous system can be used for topical diagnosis of adrenal and extraadrenal pheochromocytoma.}
journal = []
volume = {29:11}
journal type = {AC}
place = {USSR}
year = {1984}
month = {Nov}
}