Abstract
The purpose of the present study is to clarify the relationship among clinical severity of dementia, associated clinical symptoms and degree of brain atrophy. The subjects of this study were 109 demented patients with clinical diagnosis of Alzheimer type dementia. The age of them ranged from 51 years to 87 years with mean age of 71.8 +- 8.8 years. Clinical severity of dementia was evaluated by using Clinical Dementia Rating (CDR) by Hughes et al. Intellectual impairment was assessed psychologically by Hasagawa's dementia scale which was one of the standardized psychometric tests for the elderly with dementia in Japan. Brain atrophy was estimated in the three computed tomographic sections. They were the section through anterior and posterior horns of lateral ventricles, the section through cellae mediae of lateral ventricles and the section through cortex. Degree of brain atrophy was evaluated by two indexes, that is, CSF% and half width full max (HWFM) obtained from the pixel number and CT number histogram in each section, which were considered to correspond to the enlargement of the free space and mainly to the cortical atrophy, respectively. The analysis of the relationship between clinical symptoms and HWFM showed that the HWFM in the section
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Imai, Yukimichi;
Honma, Akira;
Hasegawa, Kazuo;
Inada, Yoichi
[1]
- St. Marianna Univ. School of Medicine, Kanagawa (Japan)
Citation Formats
Imai, Yukimichi, Honma, Akira, Hasegawa, Kazuo, and Inada, Yoichi.
Neuropsychiatric symptoms and CT findings in Alzheimer type dementia clinicoradiological correlation.
Japan: N. p.,
1984.
Web.
Imai, Yukimichi, Honma, Akira, Hasegawa, Kazuo, & Inada, Yoichi.
Neuropsychiatric symptoms and CT findings in Alzheimer type dementia clinicoradiological correlation.
Japan.
Imai, Yukimichi, Honma, Akira, Hasegawa, Kazuo, and Inada, Yoichi.
1984.
"Neuropsychiatric symptoms and CT findings in Alzheimer type dementia clinicoradiological correlation."
Japan.
@misc{etde_5677493,
title = {Neuropsychiatric symptoms and CT findings in Alzheimer type dementia clinicoradiological correlation}
author = {Imai, Yukimichi, Honma, Akira, Hasegawa, Kazuo, and Inada, Yoichi}
abstractNote = {The purpose of the present study is to clarify the relationship among clinical severity of dementia, associated clinical symptoms and degree of brain atrophy. The subjects of this study were 109 demented patients with clinical diagnosis of Alzheimer type dementia. The age of them ranged from 51 years to 87 years with mean age of 71.8 +- 8.8 years. Clinical severity of dementia was evaluated by using Clinical Dementia Rating (CDR) by Hughes et al. Intellectual impairment was assessed psychologically by Hasagawa's dementia scale which was one of the standardized psychometric tests for the elderly with dementia in Japan. Brain atrophy was estimated in the three computed tomographic sections. They were the section through anterior and posterior horns of lateral ventricles, the section through cellae mediae of lateral ventricles and the section through cortex. Degree of brain atrophy was evaluated by two indexes, that is, CSF% and half width full max (HWFM) obtained from the pixel number and CT number histogram in each section, which were considered to correspond to the enlargement of the free space and mainly to the cortical atrophy, respectively. The analysis of the relationship between clinical symptoms and HWFM showed that the HWFM in the section through lateral ventricles was more increased in the patients with incontinence and personality change, compared with the patients without those symptoms. Also, the HWFM in the cortex slice was more increased in the patients with perseveration, compared with the patients without perseveration. The above mentioned results seem to indicate the relationship between the degree of brain atrophy by CT and characteristic symptoms which are likely to be specific to each stage of dementia. The clinical implications of these results were discussed.}
journal = []
volume = {21:2}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Mar}
}
title = {Neuropsychiatric symptoms and CT findings in Alzheimer type dementia clinicoradiological correlation}
author = {Imai, Yukimichi, Honma, Akira, Hasegawa, Kazuo, and Inada, Yoichi}
abstractNote = {The purpose of the present study is to clarify the relationship among clinical severity of dementia, associated clinical symptoms and degree of brain atrophy. The subjects of this study were 109 demented patients with clinical diagnosis of Alzheimer type dementia. The age of them ranged from 51 years to 87 years with mean age of 71.8 +- 8.8 years. Clinical severity of dementia was evaluated by using Clinical Dementia Rating (CDR) by Hughes et al. Intellectual impairment was assessed psychologically by Hasagawa's dementia scale which was one of the standardized psychometric tests for the elderly with dementia in Japan. Brain atrophy was estimated in the three computed tomographic sections. They were the section through anterior and posterior horns of lateral ventricles, the section through cellae mediae of lateral ventricles and the section through cortex. Degree of brain atrophy was evaluated by two indexes, that is, CSF% and half width full max (HWFM) obtained from the pixel number and CT number histogram in each section, which were considered to correspond to the enlargement of the free space and mainly to the cortical atrophy, respectively. The analysis of the relationship between clinical symptoms and HWFM showed that the HWFM in the section through lateral ventricles was more increased in the patients with incontinence and personality change, compared with the patients without those symptoms. Also, the HWFM in the cortex slice was more increased in the patients with perseveration, compared with the patients without perseveration. The above mentioned results seem to indicate the relationship between the degree of brain atrophy by CT and characteristic symptoms which are likely to be specific to each stage of dementia. The clinical implications of these results were discussed.}
journal = []
volume = {21:2}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Mar}
}