Abstract
The potentiating effect of caffeine on X-ray-induced chromosomal aberrations in human blood lymphocytes has been investigated, with special reference to cell cycle stages (G0 and G2). Both quantitative and qualitative differences in the yield of chromosomal aberrations were detected in caffeine-posttreated cells, depending on the cell stage irradiated. The studies on caffeine potentiating effects on X-irradiated G0 lymphocytes from normal adults, newborns, Down syndrome patients, and an ataxia telangiectasia patient pointed to interindividual variations in the response to caffeine potentiation among normal probands and a very profound effect in ataxia cells.
Natarajan, A T;
[1]
Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands));
Obe, G;
[1]
Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands);
Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik);
Dulout, F N;
[1]
Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia))
- Rijksuniversiteit Leiden (Netherlands). Dept. of Radiation Genetics and Chemical Mutagenesis
Citation Formats
Natarajan, A T, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands)), Obe, G, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands), Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik), Dulout, F N, and Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia)).
Effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro.
Germany: N. p.,
1980.
Web.
Natarajan, A T, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands)), Obe, G, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands), Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik), Dulout, F N, & Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia)).
Effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro.
Germany.
Natarajan, A T, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands)), Obe, G, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands), Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik), Dulout, F N, and Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia)).
1980.
"Effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro."
Germany.
@misc{etde_5673507,
title = {Effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro}
author = {Natarajan, A T, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands)), Obe, G, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands), Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik), Dulout, F N, and Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia))}
abstractNote = {The potentiating effect of caffeine on X-ray-induced chromosomal aberrations in human blood lymphocytes has been investigated, with special reference to cell cycle stages (G0 and G2). Both quantitative and qualitative differences in the yield of chromosomal aberrations were detected in caffeine-posttreated cells, depending on the cell stage irradiated. The studies on caffeine potentiating effects on X-irradiated G0 lymphocytes from normal adults, newborns, Down syndrome patients, and an ataxia telangiectasia patient pointed to interindividual variations in the response to caffeine potentiation among normal probands and a very profound effect in ataxia cells.}
journal = []
volume = {54:2}
journal type = {AC}
place = {Germany}
year = {1980}
month = {Jan}
}
title = {Effect of caffeine posttreatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro}
author = {Natarajan, A T, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands)), Obe, G, Cohen (J.A.) Inst. voor Radiopathologie en Stralenbescherming, Leiden (Netherlands), Freie Univ. Berlin (Germany, F.R.). Inst. fuer Genetik), Dulout, F N, and Instituto Multidisciplinario de Biologia Celular, La Plata (Argentinia))}
abstractNote = {The potentiating effect of caffeine on X-ray-induced chromosomal aberrations in human blood lymphocytes has been investigated, with special reference to cell cycle stages (G0 and G2). Both quantitative and qualitative differences in the yield of chromosomal aberrations were detected in caffeine-posttreated cells, depending on the cell stage irradiated. The studies on caffeine potentiating effects on X-irradiated G0 lymphocytes from normal adults, newborns, Down syndrome patients, and an ataxia telangiectasia patient pointed to interindividual variations in the response to caffeine potentiation among normal probands and a very profound effect in ataxia cells.}
journal = []
volume = {54:2}
journal type = {AC}
place = {Germany}
year = {1980}
month = {Jan}
}