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Radiobiologic considerations about further development of whole-body irradiation with subsequent bone marrow transplantation applied during the treatment of acute leukemia

Journal Article:

Abstract

The results achieved hitherto with whole-body irradiation in case of acute leukemia are examined with respect to the optimization criteria of a radiotherapy. The most important failure risk is the recurrence which occurs in more than 50% of all cases, then follows the interstitial pneumonia. The authors think that an increase of the total dose, the adaption of the dose distribution to the distribution of leukemia cells in the body, and a higher fractionation of the total dose are approaches for improving the therapy results.
Publication Date:
Aug 01, 1981
Product Type:
Journal Article
Reference Number:
ERA-07-030940; EDB-82-073986
Resource Relation:
Journal Name: Strahlentherapie; (Germany, Federal Republic of); Journal Volume: 157:8
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 42 ENGINEERING; 62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; EARLY RADIATION EFFECTS; MYELOID LEUKEMIA; RADIOTHERAPY; BONE MARROW; CRITICAL ORGANS; DOSE-RESPONSE RELATIONSHIPS; FRACTIONATED IRRADIATION; GAMMA RADIATION; GAMMA SOURCES; GASTROINTESTINAL TRACT; MEV RANGE 01-10; MUCOUS MEMBRANES; PATIENTS; PHOTON BEAMS; PNEUMONIA; RADIATION DOSE DISTRIBUTIONS; RADIATION PROTECTION; SHIELDING; STEM CELLS; WHOLE-BODY IRRADIATION; ANIMAL CELLS; ANIMAL TISSUES; BEAMS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DIGESTIVE SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; ENERGY RANGE; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; HEMIC DISEASES; IONIZING RADIATIONS; IRRADIATION; LEUKEMIA; MEDICINE; MEMBRANES; MEV RANGE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIATION SOURCES; RADIATIONS; RADIOLOGY; RESPIRATORY SYSTEM; RESPIRATORY SYSTEM DISEASES; SOMATIC CELLS; THERAPY; TISSUES; 560151* - Radiation Effects on Animals- Man; 420202 - Engineering- Protective Structures & Equipment; 550603 - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
5658016
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: STRAA
Submitting Site:
DE
Size:
Pages: 537-541
Announcement Date:

Journal Article:

Citation Formats

Trott, K R, Holler, E, and Kolb, H J. Radiobiologic considerations about further development of whole-body irradiation with subsequent bone marrow transplantation applied during the treatment of acute leukemia. Germany: N. p., 1981. Web.
Trott, K R, Holler, E, & Kolb, H J. Radiobiologic considerations about further development of whole-body irradiation with subsequent bone marrow transplantation applied during the treatment of acute leukemia. Germany.
Trott, K R, Holler, E, and Kolb, H J. 1981. "Radiobiologic considerations about further development of whole-body irradiation with subsequent bone marrow transplantation applied during the treatment of acute leukemia." Germany.
@misc{etde_5658016,
title = {Radiobiologic considerations about further development of whole-body irradiation with subsequent bone marrow transplantation applied during the treatment of acute leukemia}
author = {Trott, K R, Holler, E, and Kolb, H J}
abstractNote = {The results achieved hitherto with whole-body irradiation in case of acute leukemia are examined with respect to the optimization criteria of a radiotherapy. The most important failure risk is the recurrence which occurs in more than 50% of all cases, then follows the interstitial pneumonia. The authors think that an increase of the total dose, the adaption of the dose distribution to the distribution of leukemia cells in the body, and a higher fractionation of the total dose are approaches for improving the therapy results.}
journal = {Strahlentherapie; (Germany, Federal Republic of)}
volume = {157:8}
journal type = {AC}
place = {Germany}
year = {1981}
month = {Aug}
}