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Comparison of /sup 133/Xe washout curves after bolus inhalation, perfusion, and equilibration

Journal Article:

Abstract

In 6 healthy subjects and 13 patients with chronic obstructive lung disease, /sup 133/Xe washout curves after bolus inhalation, perfusion and equilibration were compared, using a gamma camera and computerized data handling. In healthy subjects the washout after equilibration was significantly slower than after the two other procedures. As this phenomenon occurred at the basal zones, it was attributed to the presence of airway closure in some units. In patients, the three washouts were significantly different from each other. This indicated the existence of intraregional inhomogeneity in ventilation, perfusion and ventilation-perfusion ratio. Our conclusion is that comparison of these different washout methods yields valuable information not only on absolute values of pulmonary function but also on the intraregional distribution, which cannot be obtained by other examinations.
Publication Date:
Jan 01, 1978
Product Type:
Journal Article
Reference Number:
EDB-80-036982
Resource Relation:
Journal Name: Respiration; (Switzerland); Journal Volume: 35:2
Subject:
59 BASIC BIOLOGICAL SCIENCES; 62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; SCINTISCANNING; RESPIRATORY SYSTEM DISEASES; DIAGNOSIS; XENON 133; BLOOD FLOW; COMPARATIVE EVALUATIONS; INHALATION; LUNG CLEARANCE; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CLEARANCE; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; EVEN-ODD NUCLEI; EXCRETION; INTAKE; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; XENON ISOTOPES; 551001* - Physiological Systems- Tracer Techniques; 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5657903
Research Organizations:
Afdeling Nucleaire Geneeskunde, Pellenberg, Germany
Country of Origin:
Switzerland
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: RESPB
Submitting Site:
TIC
Size:
Pages: 115-121
Announcement Date:

Journal Article:

Citation Formats

Devos, P, Demedts, M, Vandecruys, A, Cosemans, J, and De Roo, M. Comparison of /sup 133/Xe washout curves after bolus inhalation, perfusion, and equilibration. Switzerland: N. p., 1978. Web.
Devos, P, Demedts, M, Vandecruys, A, Cosemans, J, & De Roo, M. Comparison of /sup 133/Xe washout curves after bolus inhalation, perfusion, and equilibration. Switzerland.
Devos, P, Demedts, M, Vandecruys, A, Cosemans, J, and De Roo, M. 1978. "Comparison of /sup 133/Xe washout curves after bolus inhalation, perfusion, and equilibration." Switzerland.
@misc{etde_5657903,
title = {Comparison of /sup 133/Xe washout curves after bolus inhalation, perfusion, and equilibration}
author = {Devos, P, Demedts, M, Vandecruys, A, Cosemans, J, and De Roo, M}
abstractNote = {In 6 healthy subjects and 13 patients with chronic obstructive lung disease, /sup 133/Xe washout curves after bolus inhalation, perfusion and equilibration were compared, using a gamma camera and computerized data handling. In healthy subjects the washout after equilibration was significantly slower than after the two other procedures. As this phenomenon occurred at the basal zones, it was attributed to the presence of airway closure in some units. In patients, the three washouts were significantly different from each other. This indicated the existence of intraregional inhomogeneity in ventilation, perfusion and ventilation-perfusion ratio. Our conclusion is that comparison of these different washout methods yields valuable information not only on absolute values of pulmonary function but also on the intraregional distribution, which cannot be obtained by other examinations.}
journal = {Respiration; (Switzerland)}
volume = {35:2}
journal type = {AC}
place = {Switzerland}
year = {1978}
month = {Jan}
}