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Applications of /sup 43/Ca, /sup 25/Mg, and /sup 67/Zn NMR spectroscopies to biological systems

Abstract

/sup 43/Ca, /sup 25/Mg and /sup 67/Zn NMR spectroscopies applied to biologically important systems are summarized mainly on the basis of our findings. It was found from our studies that (1) /sup 25/Mg NMR can be utilized for studying the dynamic and/or static behavior of Mg/sup 2 +/ in the Mg/sup 2 +/ -ATP (ADP)-kinase ternary complexes and (2) /sup 67/Zn NMR bands of diluted Zn/sup 2 +/ are much narrower than predicted and thus can be applicable for studying the dynamic and/or static behavior of Zn/sup 2 +/ in Zn/sup 2 +/ -enzyme solutions. In addition, /sup 43/Ca NMR spectra were successfully applied to some Ca/sup 2 +/ -binding proteins. In concluding remarks, we discussed possibilities of applications of those metal NMR spectroscopies to medical purposes.
Authors:
Shimizu, Tohru; Hatano, Masahiro [1] 
  1. Tohoku Univ., Sendai (Japan). Chemical Research Inst. of Non-Aqueous Solutions
Publication Date:
Dec 01, 1983
Product Type:
Journal Article
Reference Number:
AIX-16-030783; EDB-85-106294
Resource Relation:
Journal Name: NMR Igaku; (Japan); Journal Volume: 3:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CALCIUM 43; DIAGNOSTIC USES; METABOLISM; NUCLEAR MAGNETIC RESONANCE; ZINC 67; BIOCHEMISTRY; CALCIUM COMPOUNDS; CONCANAVALIN; INSULIN; MAGNESIUM 25; MAGNESIUM COMPOUNDS; NMR SPECTRA; PEPTIDE HYDROLASES; PHOSPHOTRANSFERASES; PROTEINS; USES; ZINC COMPOUNDS; AGGLUTININS; ALKALINE EARTH ISOTOPES; ALKALINE EARTH METAL COMPOUNDS; ANTIBODIES; CALCIUM ISOTOPES; CHEMISTRY; ENZYMES; EVEN-ODD NUCLEI; HEMAGGLUTININS; HORMONES; HYDROLASES; INTERMEDIATE MASS NUCLEI; ISOTOPES; LIGHT NUCLEI; MAGNESIUM ISOTOPES; MAGNETIC RESONANCE; NUCLEI; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PHOSPHORUS-GROUP TRANSFERASES; RESONANCE; SPECTRA; STABLE ISOTOPES; TRANSFERASES; ZINC ISOTOPES; 550600* - Medicine; 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5655423
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NMRIE
Submitting Site:
HEDB
Size:
Pages: 38-45
Announcement Date:
Apr 01, 1985

Citation Formats

Shimizu, Tohru, and Hatano, Masahiro. Applications of /sup 43/Ca, /sup 25/Mg, and /sup 67/Zn NMR spectroscopies to biological systems. Japan: N. p., 1983. Web.
Shimizu, Tohru, & Hatano, Masahiro. Applications of /sup 43/Ca, /sup 25/Mg, and /sup 67/Zn NMR spectroscopies to biological systems. Japan.
Shimizu, Tohru, and Hatano, Masahiro. 1983. "Applications of /sup 43/Ca, /sup 25/Mg, and /sup 67/Zn NMR spectroscopies to biological systems." Japan.
@misc{etde_5655423,
title = {Applications of /sup 43/Ca, /sup 25/Mg, and /sup 67/Zn NMR spectroscopies to biological systems}
author = {Shimizu, Tohru, and Hatano, Masahiro}
abstractNote = {/sup 43/Ca, /sup 25/Mg and /sup 67/Zn NMR spectroscopies applied to biologically important systems are summarized mainly on the basis of our findings. It was found from our studies that (1) /sup 25/Mg NMR can be utilized for studying the dynamic and/or static behavior of Mg/sup 2 +/ in the Mg/sup 2 +/ -ATP (ADP)-kinase ternary complexes and (2) /sup 67/Zn NMR bands of diluted Zn/sup 2 +/ are much narrower than predicted and thus can be applicable for studying the dynamic and/or static behavior of Zn/sup 2 +/ in Zn/sup 2 +/ -enzyme solutions. In addition, /sup 43/Ca NMR spectra were successfully applied to some Ca/sup 2 +/ -binding proteins. In concluding remarks, we discussed possibilities of applications of those metal NMR spectroscopies to medical purposes.}
journal = []
volume = {3:1}
journal type = {AC}
place = {Japan}
year = {1983}
month = {Dec}
}