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Rhodium(III) as a potentiator of the effects of X-rays on cells

Abstract

A rhodium compound, Rh(NH/sub 3/)/sub 3/Cl/sub 3/, does not sensitize the spores of Bacillus megaterium to X-rays. However, it is a very effective sensitizer of vegetative cells of Staphylococcus aureus, raising the sensitivity four times in O/sub 2/ and over 100 times in anoxia. The inhibition by oxygen of the sensitizing action of Rh(III), which operates over a wide range of (O/sub 2/), is noteworthy. These experiments were performed in saline-phosphate buffer using 50 kVp X-rays. The results are discussed in terms of the known radiation chemistry of this compound.
Publication Date:
Aug 01, 1986
Product Type:
Journal Article
Reference Number:
GBN-86-004029; EDB-88-021419
Resource Relation:
Journal Name: Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.; (United Kingdom); Journal Volume: 50:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; RADIOSENSITIZERS; RHODIUM CHLORIDES; AMMONIUM COMPLEXES; ANOXIA; BACILLUS MEGATERIUM; BACTERIAL SPORES; RESPONSE MODIFYING FACTORS; STAPHYLOCOCCUS; X RADIATION; BACILLUS; BACTERIA; CHLORIDES; CHLORINE COMPOUNDS; COMPLEXES; DRUGS; ELECTROMAGNETIC RADIATION; HALIDES; HALOGEN COMPOUNDS; IONIZING RADIATIONS; MICROORGANISMS; RADIATIONS; REFRACTORY METAL COMPOUNDS; RHODIUM COMPOUNDS; SPORES; TRANSITION ELEMENT COMPOUNDS; 560120* - Radiation Effects on Biochemicals, Cells, & Tissue Culture
OSTI ID:
5623891
Research Organizations:
Dartmouth-Hitchcock Medical Center, Hanover, NH, US. Norris Cotton Cancer Center; Texas Univ., Austin, USA. Lab. of Radiation Biology
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IJRBA
Submitting Site:
GBN
Size:
Pages: 337-343
Announcement Date:

Citation Formats

Richmond, R C, Centilli, M A, Cross, M H, and Powers, E L. Rhodium(III) as a potentiator of the effects of X-rays on cells. United Kingdom: N. p., 1986. Web. doi:10.1080/09553008614550711.
Richmond, R C, Centilli, M A, Cross, M H, & Powers, E L. Rhodium(III) as a potentiator of the effects of X-rays on cells. United Kingdom. doi:10.1080/09553008614550711.
Richmond, R C, Centilli, M A, Cross, M H, and Powers, E L. 1986. "Rhodium(III) as a potentiator of the effects of X-rays on cells." United Kingdom. doi:10.1080/09553008614550711. https://www.osti.gov/servlets/purl/10.1080/09553008614550711.
@misc{etde_5623891,
title = {Rhodium(III) as a potentiator of the effects of X-rays on cells}
author = {Richmond, R C, Centilli, M A, Cross, M H, and Powers, E L}
abstractNote = {A rhodium compound, Rh(NH/sub 3/)/sub 3/Cl/sub 3/, does not sensitize the spores of Bacillus megaterium to X-rays. However, it is a very effective sensitizer of vegetative cells of Staphylococcus aureus, raising the sensitivity four times in O/sub 2/ and over 100 times in anoxia. The inhibition by oxygen of the sensitizing action of Rh(III), which operates over a wide range of (O/sub 2/), is noteworthy. These experiments were performed in saline-phosphate buffer using 50 kVp X-rays. The results are discussed in terms of the known radiation chemistry of this compound.}
doi = {10.1080/09553008614550711}
journal = {Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.; (United Kingdom)}
volume = {50:2}
journal type = {AC}
place = {United Kingdom}
year = {1986}
month = {Aug}
}