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Bioavailability of two oral formulations of triazolam using radioreceptor assay

Journal Article:

Abstract

The radioreceptor assay (RRA) was used to quantitate plasma triazolam concentration in eight female volunteers following single 0.5 mg doses of two tablet formulations in a cross-over study. Bioavailability in terms of area under the plasma concentration versus time curve, maximum plasma concentration, time to maximum, and mean residence time was not statistically significantly different from one formulation to the other.
Publication Date:
Apr 01, 1986
Product Type:
Journal Article
Reference Number:
EDB-86-138423
Resource Relation:
Journal Name: Pharmazie; (Germany, Federal Republic of); Journal Volume: 41:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HYPNOTICS AND SEDATIVES; BIOLOGICAL AVAILABILITY; RADIORECEPTOR ASSAY; BIOCHEMICAL REACTION KINETICS; ORAL ADMINISTRATION; TRITIUM COMPOUNDS; WOMEN; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRUGS; FEMALES; ISOTOPE APPLICATIONS; KINETICS; LABELLED COMPOUNDS; MAMMALS; MAN; PRIMATES; REACTION KINETICS; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5578391
Research Organizations:
Research Institute for Pharmacy and Biochemistry, Prague, Czechoslovakia
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: PHARA
Submitting Site:
INIS
Size:
Pages: 256-257
Announcement Date:

Journal Article:

Citation Formats

Lapka, R, Cepelakova, H, Rejholec, V, and Franc, Z. Bioavailability of two oral formulations of triazolam using radioreceptor assay. Germany: N. p., 1986. Web.
Lapka, R, Cepelakova, H, Rejholec, V, & Franc, Z. Bioavailability of two oral formulations of triazolam using radioreceptor assay. Germany.
Lapka, R, Cepelakova, H, Rejholec, V, and Franc, Z. 1986. "Bioavailability of two oral formulations of triazolam using radioreceptor assay." Germany.
@misc{etde_5578391,
title = {Bioavailability of two oral formulations of triazolam using radioreceptor assay}
author = {Lapka, R, Cepelakova, H, Rejholec, V, and Franc, Z}
abstractNote = {The radioreceptor assay (RRA) was used to quantitate plasma triazolam concentration in eight female volunteers following single 0.5 mg doses of two tablet formulations in a cross-over study. Bioavailability in terms of area under the plasma concentration versus time curve, maximum plasma concentration, time to maximum, and mean residence time was not statistically significantly different from one formulation to the other.}
journal = {Pharmazie; (Germany, Federal Republic of)}
volume = {41:4}
journal type = {AC}
place = {Germany}
year = {1986}
month = {Apr}
}