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Gastric emptying time (GET) with Tc-99m-labeled semisolid meal in diabetic patients

Journal Article:

Abstract

Measurement of gastric emptying in diabetic gastroenteropathy is of interest because of the gastric atony that may produce signs and symptoms of visceral neuropathy. The purpose of this study is to present the result of GET measurements in diabetic patients. The correlation between GET and complications, fasting blood sugar (FBS), duration of disease, age, sex, and HbAlc was evaluated. Included in this study were 21 diabetic patients. Fourteen patients had diabetic complications such as peripheral neuropathy, autonomic neuropathy, nephropathy and retinopathy. Following an overnight fast, semisolid test meal mixed with 200 uCi of Tc-99m Sn-colloid was ingested by the patients. In nine normal volunteers, the GET range previously established by this method in our institution was from 47 to 78 minutes (mean 62.5 +- 7.7). In the patients with diabetic complication, particulary with triopathy, GET was significantly prolonged compared to those of normal subjects and diabetic patients without complication. On the contrary, four out of seven patients without complications, showed rapid emptying than normal subjects. This rapid emptying may reveal the early stage of pathophysiological change in diabetics. No correlation between GET and FBS, duration of disease, age, sex and HbAlc was seen. This test of radiolabeled semisolid meal was  More>>
Authors:
Tada, Akira; Koizumi, Kiyoshi; Aburano, Tamio; Bunko, Hisashi; Tonami, Norihisa [1] 
  1. Kanazawa Univ. (Japan). School of Medicine
Publication Date:
Jan 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-038631; EDB-85-126165
Resource Relation:
Journal Name: Kaku Igaku; (Japan); Journal Volume: 21:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; STOMACH; SCINTISCANNING; TECHNETIUM 99; DIAGNOSTIC USES; BIOLOGICAL FUNCTIONS; DIABETES MELLITUS; EXCRETION; ISOMERIC NUCLEI; PATIENTS; RADIOCOLLOIDS; TIME DEPENDENCE; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CLEARANCE; COLLOIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; ENDOCRINE DISEASES; FUNCTIONS; GASTROINTESTINAL TRACT; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; METABOLIC DISEASES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; USES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5568181
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: KAIGB
Submitting Site:
HEDB
Size:
Pages: 19-26
Announcement Date:

Journal Article:

Citation Formats

Tada, Akira, Koizumi, Kiyoshi, Aburano, Tamio, Bunko, Hisashi, and Tonami, Norihisa. Gastric emptying time (GET) with Tc-99m-labeled semisolid meal in diabetic patients. Japan: N. p., 1984. Web.
Tada, Akira, Koizumi, Kiyoshi, Aburano, Tamio, Bunko, Hisashi, & Tonami, Norihisa. Gastric emptying time (GET) with Tc-99m-labeled semisolid meal in diabetic patients. Japan.
Tada, Akira, Koizumi, Kiyoshi, Aburano, Tamio, Bunko, Hisashi, and Tonami, Norihisa. 1984. "Gastric emptying time (GET) with Tc-99m-labeled semisolid meal in diabetic patients." Japan.
@misc{etde_5568181,
title = {Gastric emptying time (GET) with Tc-99m-labeled semisolid meal in diabetic patients}
author = {Tada, Akira, Koizumi, Kiyoshi, Aburano, Tamio, Bunko, Hisashi, and Tonami, Norihisa}
abstractNote = {Measurement of gastric emptying in diabetic gastroenteropathy is of interest because of the gastric atony that may produce signs and symptoms of visceral neuropathy. The purpose of this study is to present the result of GET measurements in diabetic patients. The correlation between GET and complications, fasting blood sugar (FBS), duration of disease, age, sex, and HbAlc was evaluated. Included in this study were 21 diabetic patients. Fourteen patients had diabetic complications such as peripheral neuropathy, autonomic neuropathy, nephropathy and retinopathy. Following an overnight fast, semisolid test meal mixed with 200 uCi of Tc-99m Sn-colloid was ingested by the patients. In nine normal volunteers, the GET range previously established by this method in our institution was from 47 to 78 minutes (mean 62.5 +- 7.7). In the patients with diabetic complication, particulary with triopathy, GET was significantly prolonged compared to those of normal subjects and diabetic patients without complication. On the contrary, four out of seven patients without complications, showed rapid emptying than normal subjects. This rapid emptying may reveal the early stage of pathophysiological change in diabetics. No correlation between GET and FBS, duration of disease, age, sex and HbAlc was seen. This test of radiolabeled semisolid meal was found to provide a convenient, safe and effective diagnostic tool to examine gastric emptying function in diabetic patients.}
journal = {Kaku Igaku; (Japan)}
volume = {21:1}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Jan}
}