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Single photon emission tomography using sup(99m)Tc-HM-PAO in the investigation of dementia

Abstract

Single photon emission tomographic imaging of the brain using sup(99m)Tc HM-PAO was carried out in patients with a clinical diagnosis of Alzheimer's disease, non-Alzheimer frontal-lobe dementia, and progressive supranuclear palsy. Independent assessment of reductions in uptake revealed posterior hemisphere abnormalities in the majority of the Alzheimer group, and selective anterior hemisphere abnormalities in both other groups. The findings were consistent with observed patterns of mental impairment. The imaging technique has potential value in the differential diagnosis of primary cerebral atrophy.
Publication Date:
Sep 01, 1987
Product Type:
Journal Article
Reference Number:
GBN-87-007612; EDB-88-030925
Resource Relation:
Journal Name: J. Neurol., Neurosurg., Psychiatr.; (United Kingdom); Journal Volume: 50:9
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; NERVOUS SYSTEM DISEASES; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5562687
Research Organizations:
Royal Infirmary, Manchester, UK
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JNNPA
Submitting Site:
GBN
Size:
Pages: 1101-1109
Announcement Date:
Jan 01, 1988

Citation Formats

Neary, D, Snowden, J S, Shields, R A, Burjan, A W.I., Northen, B, Macdermott, N, Prescott, M C, and Testa, H J. Single photon emission tomography using sup(99m)Tc-HM-PAO in the investigation of dementia. United Kingdom: N. p., 1987. Web.
Neary, D, Snowden, J S, Shields, R A, Burjan, A W.I., Northen, B, Macdermott, N, Prescott, M C, & Testa, H J. Single photon emission tomography using sup(99m)Tc-HM-PAO in the investigation of dementia. United Kingdom.
Neary, D, Snowden, J S, Shields, R A, Burjan, A W.I., Northen, B, Macdermott, N, Prescott, M C, and Testa, H J. 1987. "Single photon emission tomography using sup(99m)Tc-HM-PAO in the investigation of dementia." United Kingdom.
@misc{etde_5562687,
title = {Single photon emission tomography using sup(99m)Tc-HM-PAO in the investigation of dementia}
author = {Neary, D, Snowden, J S, Shields, R A, Burjan, A W.I., Northen, B, Macdermott, N, Prescott, M C, and Testa, H J}
abstractNote = {Single photon emission tomographic imaging of the brain using sup(99m)Tc HM-PAO was carried out in patients with a clinical diagnosis of Alzheimer's disease, non-Alzheimer frontal-lobe dementia, and progressive supranuclear palsy. Independent assessment of reductions in uptake revealed posterior hemisphere abnormalities in the majority of the Alzheimer group, and selective anterior hemisphere abnormalities in both other groups. The findings were consistent with observed patterns of mental impairment. The imaging technique has potential value in the differential diagnosis of primary cerebral atrophy.}
journal = []
volume = {50:9}
journal type = {AC}
place = {United Kingdom}
year = {1987}
month = {Sep}
}