You need JavaScript to view this

Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man

Abstract

Emission computed tomography with technetium-99m pyrophosphate was used to delineate the location and estimate the size of myocardial infarcts in 20 patients with documented acute myocardial infarction. Tomography was performed after planar imaging within 2-5 days after the onset of infarction. Infarct volume was measured from the tomographic images by computerised planimetry and compared with the cumulative release of creatine kinase MB isoenzyme. The planar images showed discrete myocardial uptake in 13 of the 20 patients and diffuse uptake throughout the cardiac region in the remaining seven. In contrast, the tomographic images clearly delineated myocardial uptake by avoiding confusion of myocardial activity with that of surrounding structures, particularly bones, in all patients. For the 10 patients whose infarct size was assessed by analysis of the creatine kinase MB curve there was a close correlation between infarct volume estimated by tomography and by cumulative creatine kinase MB release. Thus emission computed tomography can provide a three dimensional map of technetium-99m pyrophosphate distribution within the heart and is thus able accurately to localise and estimate the size of myocardial infarcts in man.
Authors:
Tamaki, S; Kadota, K; Kambara, H; Suzuki, Y; Nohara, R; Murakami, T; Kawai, C; Tamaki, N; Torizuka, K [1] 
  1. Kyoto Univ. (Japan). Faculty of Medicine
Publication Date:
Jul 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-017874; EDB-85-097520
Resource Relation:
Journal Name: Br. Heart J.; (United Kingdom); Journal Volume: 52:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MYOCARDIAL INFARCTION; DIAGNOSIS; MYOCARDIUM; EMISSION COMPUTED TOMOGRAPHY; CREATINE; ISOENZYMES; ISOMERIC NUCLEI; PHOSPHOTRANSFERASES; TECHNETIUM 99; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; ENZYMES; HEART; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PHOSPHORUS-GROUP TRANSFERASES; RADIOISOTOPES; TECHNETIUM ISOTOPES; TOMOGRAPHY; TRANSFERASES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5557328
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: BHJUA
Submitting Site:
HEDB
Size:
Pages: 30-37
Announcement Date:
Feb 01, 1985

Citation Formats

Tamaki, S, Kadota, K, Kambara, H, Suzuki, Y, Nohara, R, Murakami, T, Kawai, C, Tamaki, N, and Torizuka, K. Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man. United Kingdom: N. p., 1984. Web. doi:10.1136/hrt.52.1.30.
Tamaki, S, Kadota, K, Kambara, H, Suzuki, Y, Nohara, R, Murakami, T, Kawai, C, Tamaki, N, & Torizuka, K. Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man. United Kingdom. https://doi.org/10.1136/hrt.52.1.30
Tamaki, S, Kadota, K, Kambara, H, Suzuki, Y, Nohara, R, Murakami, T, Kawai, C, Tamaki, N, and Torizuka, K. 1984. "Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man." United Kingdom. https://doi.org/10.1136/hrt.52.1.30.
@misc{etde_5557328,
title = {Emission computed tomography with technetium-99m pyrophosphate for delineating location and size of acute myocardial infarction in man}
author = {Tamaki, S, Kadota, K, Kambara, H, Suzuki, Y, Nohara, R, Murakami, T, Kawai, C, Tamaki, N, and Torizuka, K}
abstractNote = {Emission computed tomography with technetium-99m pyrophosphate was used to delineate the location and estimate the size of myocardial infarcts in 20 patients with documented acute myocardial infarction. Tomography was performed after planar imaging within 2-5 days after the onset of infarction. Infarct volume was measured from the tomographic images by computerised planimetry and compared with the cumulative release of creatine kinase MB isoenzyme. The planar images showed discrete myocardial uptake in 13 of the 20 patients and diffuse uptake throughout the cardiac region in the remaining seven. In contrast, the tomographic images clearly delineated myocardial uptake by avoiding confusion of myocardial activity with that of surrounding structures, particularly bones, in all patients. For the 10 patients whose infarct size was assessed by analysis of the creatine kinase MB curve there was a close correlation between infarct volume estimated by tomography and by cumulative creatine kinase MB release. Thus emission computed tomography can provide a three dimensional map of technetium-99m pyrophosphate distribution within the heart and is thus able accurately to localise and estimate the size of myocardial infarcts in man.}
doi = {10.1136/hrt.52.1.30}
journal = []
volume = {52:1}
journal type = {AC}
place = {United Kingdom}
year = {1984}
month = {Jul}
}