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Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography

Journal Article:

Abstract

Although metrizamide is now being superseded by other contrast media, the mechanisms of its side effects may be of fundamental importance. One hundered and four consecutive patients with suspected cervical cord or root lesion were studied prospectively for factors which might influence the side effects of metrizamide myelography. Elderly patients were more prone to develop mental confusion. An earlier onset of dizziness and/or vertigo was associated with the lumbar route of intrathecal injection. Perhaps surprisingly, phenobarbitone prophylaxis shortened the duration of confusion and delayed the onset of headaches. Other factors, viz. sex, excess intracranial flow of metrizamide and myelographic blockage were not shown to have a signifiant influence on the adverse reactions.
Publication Date:
Jul 01, 1986
Product Type:
Journal Article
Reference Number:
DEN-86-007541; EDB-86-138606
Resource Relation:
Journal Name: Neuroradiology; (Germany, Federal Republic of); Journal Volume: 28:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; METRIZAMIDE; SIDE EFFECTS; BIOMEDICAL RADIOGRAPHY; HEAD; IMAGES; INJURIES; MENTAL DISORDERS; PAIN; PATIENTS; SPINAL CORD; X-RAY RADIOGRAPHY; AMIDES; BODY; BODY AREAS; CENTRAL NERVOUS SYSTEM; CONTRAST MEDIA; DIAGNOSTIC TECHNIQUES; INDUSTRIAL RADIOGRAPHY; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIOLOGY; SYMPTOMS; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5527263
Research Organizations:
National Hospital for Nervous Diseases, London, UK. Lysholm Radiological Dept.
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NRDYA
Submitting Site:
DEN
Size:
Pages: 339-343
Announcement Date:

Journal Article:

Citation Formats

Yu, Y L, Du Boulay, G H, and Paul, E. Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography. Germany: N. p., 1986. Web.
Yu, Y L, Du Boulay, G H, & Paul, E. Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography. Germany.
Yu, Y L, Du Boulay, G H, and Paul, E. 1986. "Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography." Germany.
@misc{etde_5527263,
title = {Influence of certain factors on the manifestations of the adverse effects of metrizamide myelography}
author = {Yu, Y L, Du Boulay, G H, and Paul, E}
abstractNote = {Although metrizamide is now being superseded by other contrast media, the mechanisms of its side effects may be of fundamental importance. One hundered and four consecutive patients with suspected cervical cord or root lesion were studied prospectively for factors which might influence the side effects of metrizamide myelography. Elderly patients were more prone to develop mental confusion. An earlier onset of dizziness and/or vertigo was associated with the lumbar route of intrathecal injection. Perhaps surprisingly, phenobarbitone prophylaxis shortened the duration of confusion and delayed the onset of headaches. Other factors, viz. sex, excess intracranial flow of metrizamide and myelographic blockage were not shown to have a signifiant influence on the adverse reactions.}
journal = {Neuroradiology; (Germany, Federal Republic of)}
volume = {28:4}
journal type = {AC}
place = {Germany}
year = {1986}
month = {Jul}
}