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Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines

Abstract

The expression of the intercellular adhesion molecule-1 (ICAM-1) and neural cell adhesion molecule (NCAM) by glioma cell lines was investigated. The effects of interferon (IFN)-[gamma] or irradiation on the expression was also assessed. Two glioma cell lines showed more than 75% NCAM-positive cells. After treatment with IFN-[gamma] or irradiation, another three cell lines were induced to show more than 50% positive cells. Three glioma cell lines showed more than 50% ICAM-1-positive cells. After treatment with IFN-[gamma], another two cell lines were induced to show more than 50% positive cells. After treatment with irradiation, one more cell line was induced to show more than 50% positive cells. ICAM-1 and NCAM expression by glioma cell lines is susceptible to modulation by IFN-[gamma] or irradiation. (author).
Authors:
Yamanaka, Ryuya; Tanaka, Ryuichi; Yoshida, Seiichi [1] 
  1. Niigata Univ. (Japan). Brain Research Inst.
Publication Date:
Nov 01, 1993
Product Type:
Journal Article
Reference Number:
JPN-93-012273; EDB-94-027167
Resource Relation:
Journal Name: Neurologia Medico-Chirurgica; (Japan); Journal Volume: 33:11
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; MOLECULES; BIOLOGICAL RADIATION EFFECTS; ADHESION; CELL CULTURES; CELL FLOW SYSTEMS; GLIOMAS; GLYCOPROTEINS; IMMUNITY; INTERFERON; RADIOTHERAPY; TUMOR CELLS; ANIMAL CELLS; BIOLOGICAL EFFECTS; DISEASES; GROWTH FACTORS; LYMPHOKINES; MEDICINE; MITOGENS; NEOPLASMS; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; PROTEINS; RADIATION EFFECTS; RADIOLOGY; THERAPY; 560120* - Radiation Effects on Biochemicals, Cells, & Tissue Culture
OSTI ID:
5520189
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0387-2572; CODEN: NMCHBN
Submitting Site:
JPN
Size:
Pages: 749-752
Announcement Date:
Feb 15, 1994

Citation Formats

Yamanaka, Ryuya, Tanaka, Ryuichi, and Yoshida, Seiichi. Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines. Japan: N. p., 1993. Web.
Yamanaka, Ryuya, Tanaka, Ryuichi, & Yoshida, Seiichi. Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines. Japan.
Yamanaka, Ryuya, Tanaka, Ryuichi, and Yoshida, Seiichi. 1993. "Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines." Japan.
@misc{etde_5520189,
title = {Effects of irradiation on the expression of the adhesion molecules (NCAM, ICAM-1) by glioma cell lines}
author = {Yamanaka, Ryuya, Tanaka, Ryuichi, and Yoshida, Seiichi}
abstractNote = {The expression of the intercellular adhesion molecule-1 (ICAM-1) and neural cell adhesion molecule (NCAM) by glioma cell lines was investigated. The effects of interferon (IFN)-[gamma] or irradiation on the expression was also assessed. Two glioma cell lines showed more than 75% NCAM-positive cells. After treatment with IFN-[gamma] or irradiation, another three cell lines were induced to show more than 50% positive cells. Three glioma cell lines showed more than 50% ICAM-1-positive cells. After treatment with IFN-[gamma], another two cell lines were induced to show more than 50% positive cells. After treatment with irradiation, one more cell line was induced to show more than 50% positive cells. ICAM-1 and NCAM expression by glioma cell lines is susceptible to modulation by IFN-[gamma] or irradiation. (author).}
journal = []
volume = {33:11}
journal type = {AC}
place = {Japan}
year = {1993}
month = {Nov}
}