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Effects of treatments for experimental bone tumor on prostaglandin E level and bone scintigrams

Journal Article:

Abstract

The role of Prostaglandin E (PgE) level was studied experimentally as follows: 1) intrahepatic implantation of VX-2, 2) intravenous injection of VX-2, 3) effect of treatments on intramedullary implanted VX-2. The levels of PgE in intrahepatic and intravenous transplantation were not higher than that of intramedullary transplantation. Mitomycin C (MMC) did not reduce the PgE level and appearance time of bone scan abnormality was the same as that of untreated animals. A combination of indomethacin and MMC caused a delay in appearance time of bone scan abnormalities.
Authors:
Otsuka, Nobuaki; Ito, Yasuhiko; Yoneda, Masaya; Muranaka, Akira; Nishishita, Soichi; Morita, Rikushi [1] 
  1. Kawasaki Medical School, Kurashiki, Okayama (Japan)
Publication Date:
Oct 01, 1983
Product Type:
Journal Article
Reference Number:
AIX-16-038641; EDB-85-126197
Resource Relation:
Journal Name: Kawasaki Med. J.; (Japan); Journal Volume: 9:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BONE MARROW; SCINTISCANNING; BONE TISSUES; PROSTAGLANDINS; RADIOIMMUNOASSAY; BLOOD PLASMA; CARCINOMAS; CHEMOTHERAPY; EXPERIMENTAL NEOPLASMS; MITOMYCIN; RABBITS; ANIMAL TISSUES; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIBIOTICS; ANTIMITOTIC DRUGS; ANTINEOPLASTIC DRUGS; BIOLOGICAL MATERIALS; BLOOD; BODY; BODY FLUIDS; CONNECTIVE TISSUE; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; HEMATOPOIETIC SYSTEM; ISOTOPE APPLICATIONS; MAMMALS; MATERIALS; NEOPLASMS; ORGANS; RADIOASSAY; RADIOISOTOPE SCANNING; THERAPY; TISSUES; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5519701
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: KAMJD
Submitting Site:
HEDB
Size:
Pages: 151-155
Announcement Date:
May 01, 1985

Journal Article:

Citation Formats

Otsuka, Nobuaki, Ito, Yasuhiko, Yoneda, Masaya, Muranaka, Akira, Nishishita, Soichi, and Morita, Rikushi. Effects of treatments for experimental bone tumor on prostaglandin E level and bone scintigrams. Japan: N. p., 1983. Web.
Otsuka, Nobuaki, Ito, Yasuhiko, Yoneda, Masaya, Muranaka, Akira, Nishishita, Soichi, & Morita, Rikushi. Effects of treatments for experimental bone tumor on prostaglandin E level and bone scintigrams. Japan.
Otsuka, Nobuaki, Ito, Yasuhiko, Yoneda, Masaya, Muranaka, Akira, Nishishita, Soichi, and Morita, Rikushi. 1983. "Effects of treatments for experimental bone tumor on prostaglandin E level and bone scintigrams." Japan.
@misc{etde_5519701,
title = {Effects of treatments for experimental bone tumor on prostaglandin E level and bone scintigrams}
author = {Otsuka, Nobuaki, Ito, Yasuhiko, Yoneda, Masaya, Muranaka, Akira, Nishishita, Soichi, and Morita, Rikushi}
abstractNote = {The role of Prostaglandin E (PgE) level was studied experimentally as follows: 1) intrahepatic implantation of VX-2, 2) intravenous injection of VX-2, 3) effect of treatments on intramedullary implanted VX-2. The levels of PgE in intrahepatic and intravenous transplantation were not higher than that of intramedullary transplantation. Mitomycin C (MMC) did not reduce the PgE level and appearance time of bone scan abnormality was the same as that of untreated animals. A combination of indomethacin and MMC caused a delay in appearance time of bone scan abnormalities.}
journal = {Kawasaki Med. J.; (Japan)}
volume = {9:3}
journal type = {AC}
place = {Japan}
year = {1983}
month = {Oct}
}