Abstract
In this paper some indicators of exposure of underground workers to radon in Slovakia which will be used for determination of miners radiation burden and for the radon dose estimate was explained. The projected study has a dose-effect scaffold and its projected goals are on the side of dose assessment: 1) to determine the professional exposure of underground workers to radon by personal dosimetry and to establish a database of integrated personal doses for future epidemiological studies; 2) to introduce the method of counting the radionuclide {sup 210}Pb in the bones and skulls of underground workers. On the side of effect assessment the goals are: 1) to find out if a dependence of the number of chromosomal aberrations (CA) and micronuclei in the lymphocytes from radon dose exists. The measurements of radon in mines, preferentially those by personal dosimeters as well as an existing database of radon concentration measurements in dwellings and caves will serve for the radon dose estimate; 2) to compare the DNA-repair rate in the lymphocytes of people professionally exposed to radon in Slovak caves with the same rate as assessed in unexposed people; 3) to find out the proportional role of confounding factors such as smoking,
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Beno, M;
Nikodemova, D;
Vladar, M;
Fueloep, M;
Vicanova, M
[1]
- Inst. of Preventive and Clinical Medicine, Bratislava (Slovakia)
Citation Formats
Beno, M, Nikodemova, D, Vladar, M, Fueloep, M, and Vicanova, M.
Outlines of a study of some indicators of exposure of underground workers to radon in Slovakia.
Slovakia: N. p.,
1995.
Web.
Beno, M, Nikodemova, D, Vladar, M, Fueloep, M, & Vicanova, M.
Outlines of a study of some indicators of exposure of underground workers to radon in Slovakia.
Slovakia.
Beno, M, Nikodemova, D, Vladar, M, Fueloep, M, and Vicanova, M.
1995.
"Outlines of a study of some indicators of exposure of underground workers to radon in Slovakia."
Slovakia.
@misc{etde_551065,
title = {Outlines of a study of some indicators of exposure of underground workers to radon in Slovakia}
author = {Beno, M, Nikodemova, D, Vladar, M, Fueloep, M, and Vicanova, M}
abstractNote = {In this paper some indicators of exposure of underground workers to radon in Slovakia which will be used for determination of miners radiation burden and for the radon dose estimate was explained. The projected study has a dose-effect scaffold and its projected goals are on the side of dose assessment: 1) to determine the professional exposure of underground workers to radon by personal dosimetry and to establish a database of integrated personal doses for future epidemiological studies; 2) to introduce the method of counting the radionuclide {sup 210}Pb in the bones and skulls of underground workers. On the side of effect assessment the goals are: 1) to find out if a dependence of the number of chromosomal aberrations (CA) and micronuclei in the lymphocytes from radon dose exists. The measurements of radon in mines, preferentially those by personal dosimeters as well as an existing database of radon concentration measurements in dwellings and caves will serve for the radon dose estimate; 2) to compare the DNA-repair rate in the lymphocytes of people professionally exposed to radon in Slovak caves with the same rate as assessed in unexposed people; 3) to find out the proportional role of confounding factors such as smoking, alcohol abuse, exposure to dust etc., which might influence upon the interpretation of the dose from radon to health response relationship; 4) to establish a central database of lung cancer cases in professionally exposed underground workers for future epidemiological studies. The direct method will rely upon determination of miners radiation burden based on the {sup 210}Pb activity deposited in skeleton. The experimental design to assess the effects will have three main methodological parts: 1) determination of the count of chromosomal aberrations and micronuclei using classical methods; 2) determination of the chromosomal changes using the fluorescent in situ hybridization method; 3) determination of the DNA-repair rate. (J.K.) 8 refs.}
place = {Slovakia}
year = {1995}
month = {Dec}
}
title = {Outlines of a study of some indicators of exposure of underground workers to radon in Slovakia}
author = {Beno, M, Nikodemova, D, Vladar, M, Fueloep, M, and Vicanova, M}
abstractNote = {In this paper some indicators of exposure of underground workers to radon in Slovakia which will be used for determination of miners radiation burden and for the radon dose estimate was explained. The projected study has a dose-effect scaffold and its projected goals are on the side of dose assessment: 1) to determine the professional exposure of underground workers to radon by personal dosimetry and to establish a database of integrated personal doses for future epidemiological studies; 2) to introduce the method of counting the radionuclide {sup 210}Pb in the bones and skulls of underground workers. On the side of effect assessment the goals are: 1) to find out if a dependence of the number of chromosomal aberrations (CA) and micronuclei in the lymphocytes from radon dose exists. The measurements of radon in mines, preferentially those by personal dosimeters as well as an existing database of radon concentration measurements in dwellings and caves will serve for the radon dose estimate; 2) to compare the DNA-repair rate in the lymphocytes of people professionally exposed to radon in Slovak caves with the same rate as assessed in unexposed people; 3) to find out the proportional role of confounding factors such as smoking, alcohol abuse, exposure to dust etc., which might influence upon the interpretation of the dose from radon to health response relationship; 4) to establish a central database of lung cancer cases in professionally exposed underground workers for future epidemiological studies. The direct method will rely upon determination of miners radiation burden based on the {sup 210}Pb activity deposited in skeleton. The experimental design to assess the effects will have three main methodological parts: 1) determination of the count of chromosomal aberrations and micronuclei using classical methods; 2) determination of the chromosomal changes using the fluorescent in situ hybridization method; 3) determination of the DNA-repair rate. (J.K.) 8 refs.}
place = {Slovakia}
year = {1995}
month = {Dec}
}