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Limbic system, the main focus of dementia syndrome; A study with MRI and PET

Journal Article:

Abstract

Alzheimer disease and multi-infarct dementia are two entirely different diseases producing almost the same abnormalities as dementia syndrome. The statistical studies with MRI to locate the focus of dementia syndrome in the neocortex was an absolute failure. With MRI there is drastic atrophy and destruction of the amygdala and hippocampus suggesting the limbic system as the focus of dementia syndrome. Destruction of the limbic system in particular amygdala and hippocampus produced the functional obstruction brought about by the marked reduction in the glucose utilization with PET in the bilateral temporal, parietal and occipital association cortices. Although this type constitutes only about 1/5 of all dementia patients. It is considered the fundamental type of dementia syndrome. Aside from this, there is a type wherein simultaneous and symmetrical reductions in glucose utilization of the frontal association cortex and the motor association cortex in the anterior part of the neocortex. This is referred to as type II. It constitutes about 4/5 of all dementia patients which is far more than type I. Based on these results, it is thought that limbic system is the main focus of dementia syndrome. (author).
Authors:
Matsuzawa, Taiju [1] 
  1. Morinosato Hospital, Atsugi, Kanagawa (Japan)
Publication Date:
Dec 01, 1990
Product Type:
Journal Article
Reference Number:
JPN-91-007363; EDB-91-119379
Resource Relation:
Journal Name: Science Reports of the Research Institute, Tohoku University, Series C (Medicine); (Japan); Journal Volume: 37:1-4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; NMR IMAGING; POSITRON COMPUTED TOMOGRAPHY; ATROPHY; FLUORINE 18; FLUORODEOXYGLUCOSE; GLUCOSE; MENTAL DISORDERS; ALDEHYDES; ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; BRAIN; CARBOHYDRATES; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HEXOSES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MONOSACCHARIDES; NANOSEC LIVING RADIOISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; RADIOISOTOPES; SACCHARIDES; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-); 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5507627
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0371-2761; CODEN: SRTCA
Submitting Site:
JPN
Size:
Pages: 51-56
Announcement Date:

Journal Article:

Citation Formats

Matsuzawa, Taiju. Limbic system, the main focus of dementia syndrome; A study with MRI and PET. Japan: N. p., 1990. Web.
Matsuzawa, Taiju. Limbic system, the main focus of dementia syndrome; A study with MRI and PET. Japan.
Matsuzawa, Taiju. 1990. "Limbic system, the main focus of dementia syndrome; A study with MRI and PET." Japan.
@misc{etde_5507627,
title = {Limbic system, the main focus of dementia syndrome; A study with MRI and PET}
author = {Matsuzawa, Taiju}
abstractNote = {Alzheimer disease and multi-infarct dementia are two entirely different diseases producing almost the same abnormalities as dementia syndrome. The statistical studies with MRI to locate the focus of dementia syndrome in the neocortex was an absolute failure. With MRI there is drastic atrophy and destruction of the amygdala and hippocampus suggesting the limbic system as the focus of dementia syndrome. Destruction of the limbic system in particular amygdala and hippocampus produced the functional obstruction brought about by the marked reduction in the glucose utilization with PET in the bilateral temporal, parietal and occipital association cortices. Although this type constitutes only about 1/5 of all dementia patients. It is considered the fundamental type of dementia syndrome. Aside from this, there is a type wherein simultaneous and symmetrical reductions in glucose utilization of the frontal association cortex and the motor association cortex in the anterior part of the neocortex. This is referred to as type II. It constitutes about 4/5 of all dementia patients which is far more than type I. Based on these results, it is thought that limbic system is the main focus of dementia syndrome. (author).}
journal = {Science Reports of the Research Institute, Tohoku University, Series C (Medicine); (Japan)}
volume = {37:1-4}
journal type = {AC}
place = {Japan}
year = {1990}
month = {Dec}
}