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Comparison of the immunogenic effect of rabies vaccines

Journal Article:

Abstract

Immunogenic effect of the Lyssa and Lyssavac rabies vaccines were compared in sheep. Blood samples were collected 8 times from the experimental groups of 5 animals each during a 6-month period after vaccination. The dynamics of virus neutralizing antibodies was followed and the in vitro reactions of peripheral lymphocytes were studied. In the 3rd week after vaccination the titre of virus neutralizing antibodies was higher (1:128.4) in the experimental group immunized with the Lyssavac than in that immunized with the Lyssa vaccine (1:118) and it remained also at a higher level in the 6th month after vaccination (1:50) than that of the group immunized with the latter vaccine (1:20.4). As regards the in vitro reactions of lymphocytes, no essential differences were found either in the rates of immune rosette formation or in the degree of blastogenesis measured by the incorporation of /sup 3/HTdR. The mean values of IgG and IgM positive cells were also similar in both experimental groups as it was determined by immunofluorescence.
Authors:
Kiss, Zs [1] 
  1. Allatgyogyaszati Oltoanyagellenoerzoe Intezet, Budapest (Hungary)
Publication Date:
Oct 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-13-674962; EDB-82-105048
Resource Relation:
Journal Name: Magy. Allatorv. Lapja; (Hungary); Journal Volume: 36:10
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; RABIES; VACCINES; RADIOIMMUNOASSAY; AUTORADIOGRAPHY; COMPARATIVE EVALUATIONS; LYMPHOCYTES; RADIOPHARMACEUTICALS; SAMPLE PREPARATION; SHEEP; TRITIUM COMPOUNDS; ANIMAL CELLS; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DISEASES; DOMESTIC ANIMALS; DRUGS; INFECTIOUS DISEASES; ISOTOPE APPLICATIONS; LABELLED COMPOUNDS; LEUKOCYTES; MAMMALS; MATERIALS; NERVOUS SYSTEM DISEASES; RADIOASSAY; RUMINANTS; SOMATIC CELLS; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5477732
Country of Origin:
Hungary
Language:
Hungarian
Other Identifying Numbers:
Journal ID: CODEN: MGALA
Submitting Site:
HEDB
Size:
Pages: 655-657
Announcement Date:

Journal Article:

Citation Formats

Kiss, Zs. Comparison of the immunogenic effect of rabies vaccines. Hungary: N. p., 1981. Web.
Kiss, Zs. Comparison of the immunogenic effect of rabies vaccines. Hungary.
Kiss, Zs. 1981. "Comparison of the immunogenic effect of rabies vaccines." Hungary.
@misc{etde_5477732,
title = {Comparison of the immunogenic effect of rabies vaccines}
author = {Kiss, Zs}
abstractNote = {Immunogenic effect of the Lyssa and Lyssavac rabies vaccines were compared in sheep. Blood samples were collected 8 times from the experimental groups of 5 animals each during a 6-month period after vaccination. The dynamics of virus neutralizing antibodies was followed and the in vitro reactions of peripheral lymphocytes were studied. In the 3rd week after vaccination the titre of virus neutralizing antibodies was higher (1:128.4) in the experimental group immunized with the Lyssavac than in that immunized with the Lyssa vaccine (1:118) and it remained also at a higher level in the 6th month after vaccination (1:50) than that of the group immunized with the latter vaccine (1:20.4). As regards the in vitro reactions of lymphocytes, no essential differences were found either in the rates of immune rosette formation or in the degree of blastogenesis measured by the incorporation of /sup 3/HTdR. The mean values of IgG and IgM positive cells were also similar in both experimental groups as it was determined by immunofluorescence.}
journal = {Magy. Allatorv. Lapja; (Hungary)}
volume = {36:10}
journal type = {AC}
place = {Hungary}
year = {1981}
month = {Oct}
}