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Computed tomography after administration of SMANCS-Lipiodol to liver cancers

Journal Article:

Abstract

Sixty-eight cases of liver cancer, 48 cases of hepatocellular carcinoma and 20 cases of metastatic liver cancer, were treated by injection of SMANCS-Lipiodol (S-L) via tumor feeding arteries. Abdominal CT was carried out on the 3 rd day, 1 week, 2 and 4 weeks after the administration. These CT images were compared with those before the administration. Both primary and metastatic liver cancers were visualized as high density area due to the selective stay of S-L. Thus, the method became useful as a diagnostic tool; several tumors were newly visualized after the administration. S-L stayed in primary tumors and metastatic tumors. There were three types of the remaining of S-L in metastatic tumors for a long period: Type A, in which S-L remained in entire tumors; Types B, in which it remained primarily in circumference of tumor and Mixed type of A and B. The anticancer effect of S-L paralleled with the extent of the remaining of S-L in tumors, which was classified from Grade 0 to Grade IV. Grade IV means that S-L was recognized in the entire areas of tumors in the every slice of CT, and in the Grade IV tumors size reduced effectively after several months  More>>
Authors:
Maki, Shojiro; Konno, Toshimitsu; Iwai, Ken; Uchida, Mitsukuni; Tashiro, Seiki; Miyauchi, Yoshimasa; Maeda, Hiroshi [1] 
  1. Kumamoto Univ. (Japan). School of Medicine
Publication Date:
Aug 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-054080; EDB-85-134728
Resource Relation:
Journal Name: Nippon Gan Chiryo Gakkai-Shi; (Japan); Journal Volume: 19:7
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HEPATOMAS; CHEMOTHERAPY; LIVER; CAT SCANNING; DIAGNOSIS; IMAGE PROCESSING; IMAGES; LIPIODOL; METASTASES; PATIENTS; BODY; COMPUTERIZED TOMOGRAPHY; CONTRAST MEDIA; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; NEOPLASMS; OILS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; OTHER ORGANIC COMPOUNDS; PROCESSING; THERAPY; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5475768
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NGCJA
Submitting Site:
HEDB
Size:
Pages: 1443-1449
Announcement Date:

Journal Article:

Citation Formats

Maki, Shojiro, Konno, Toshimitsu, Iwai, Ken, Uchida, Mitsukuni, Tashiro, Seiki, Miyauchi, Yoshimasa, and Maeda, Hiroshi. Computed tomography after administration of SMANCS-Lipiodol to liver cancers. Japan: N. p., 1984. Web.
Maki, Shojiro, Konno, Toshimitsu, Iwai, Ken, Uchida, Mitsukuni, Tashiro, Seiki, Miyauchi, Yoshimasa, & Maeda, Hiroshi. Computed tomography after administration of SMANCS-Lipiodol to liver cancers. Japan.
Maki, Shojiro, Konno, Toshimitsu, Iwai, Ken, Uchida, Mitsukuni, Tashiro, Seiki, Miyauchi, Yoshimasa, and Maeda, Hiroshi. 1984. "Computed tomography after administration of SMANCS-Lipiodol to liver cancers." Japan.
@misc{etde_5475768,
title = {Computed tomography after administration of SMANCS-Lipiodol to liver cancers}
author = {Maki, Shojiro, Konno, Toshimitsu, Iwai, Ken, Uchida, Mitsukuni, Tashiro, Seiki, Miyauchi, Yoshimasa, and Maeda, Hiroshi}
abstractNote = {Sixty-eight cases of liver cancer, 48 cases of hepatocellular carcinoma and 20 cases of metastatic liver cancer, were treated by injection of SMANCS-Lipiodol (S-L) via tumor feeding arteries. Abdominal CT was carried out on the 3 rd day, 1 week, 2 and 4 weeks after the administration. These CT images were compared with those before the administration. Both primary and metastatic liver cancers were visualized as high density area due to the selective stay of S-L. Thus, the method became useful as a diagnostic tool; several tumors were newly visualized after the administration. S-L stayed in primary tumors and metastatic tumors. There were three types of the remaining of S-L in metastatic tumors for a long period: Type A, in which S-L remained in entire tumors; Types B, in which it remained primarily in circumference of tumor and Mixed type of A and B. The anticancer effect of S-L paralleled with the extent of the remaining of S-L in tumors, which was classified from Grade 0 to Grade IV. Grade IV means that S-L was recognized in the entire areas of tumors in the every slice of CT, and in the Grade IV tumors size reduced effectively after several months period. The dosage which was necessary to attain Grade IV was 0.08 ml per square centimeters calculated by the largest slice of every tumor. From Grade 0 to III, they need additional administration of S-L until to attain Grade IV in the tumor for the effective tumor regression.}
journal = {Nippon Gan Chiryo Gakkai-Shi; (Japan)}
volume = {19:7}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Aug}
}