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Effect of vincristine on biodistribution of sodium pertechnetate and 99 m Tc-phytate radiopharmaceuticals in mice balb/c; Efeito da vincristina na biodistribuicao dos radiofarmacos pertecnetato de sodio e fitato marcados com Tecnecio-99m em camundongos balb/c

Abstract

Vincristine is a drug used in chemotherapy for cancer treatment. The radiopharmaceuticals biodistribution or pharmacokinetics can be modify by drugs effect, diseases, surgery and radiotherapy. The absence of knowledge of these factors may result in an unexpected behavior of the radiopharmaceuticals. In this work was studied the effect of vincristine on biodistribution of pertechnetate used for thyroid and brain scintigraphy and 99 mTc-phytate used for hepatic scintigraphy. 5 refs., 5 tabs.
Authors:
Britto, Deise M.M.; Souza Freitas, Rosemeire de; Paula, Emilio F. de; Bernardo-Filho, Mario [1] 
  1. Instituto Nacional do Cancer, Rio de Janeiro, RJ (Brazil)
Publication Date:
Dec 01, 1997
Product Type:
Miscellaneous
Report Number:
CONF-9708106-
Reference Number:
SCA: 560161; 400703; PA: AIX-28:073574; EDB-97:146769; SN: 97001879051
Resource Relation:
Conference: 4. Brazilian meeting on nuclear applications, 4. Encontro nacional de aplicacoes nucleares, Pocos de Caldas (Brazil), 18-22 Aug 1997; Other Information: DN: Conference organized jointly with the 11. National meeting on reactor physics and thermohydraulics (11. ENFIR).; PBD: 1997; Related Information: Is Part Of Proceedings of the 4. Brazilian meeting on nuclear applications. v. 2; PB: 713 p.; Anais do 4. Encontro nacional de aplicacoes nucleares. v. 2
Subject:
56 BIOLOGY AND MEDICINE, APPLIED STUDIES; 40 CHEMISTRY; RADIOPHARMACEUTICALS; RADIONUCLIDE KINETICS; BIOLOGICAL LOCALIZATION; INTRAVENOUS INJECTION; LIGANDS; MICE; ONCOVIN; PERTECHNETATES; RADIATION DOSES; RADIONUCLIDE ADMINISTRATION; RESPONSE MODIFYING FACTORS; SODIUM; TECHNETIUM 99; TISSUE DISTRIBUTION
OSTI ID:
545735
Research Organizations:
Associacao Brasileira de Energia Nuclear, Rio de Janeiro, RJ (Brazil)
Country of Origin:
Brazil
Language:
Portuguese
Other Identifying Numbers:
TRN: BR9738258073574
Availability:
Available from the library of the Brazilian Nuclear Energy Commission, Rio de Janeiro
Submitting Site:
BRN
Size:
pp. 778-780
Announcement Date:
Jan 23, 2004

Citation Formats

Britto, Deise M.M., Souza Freitas, Rosemeire de, Paula, Emilio F. de, and Bernardo-Filho, Mario. Effect of vincristine on biodistribution of sodium pertechnetate and 99 m Tc-phytate radiopharmaceuticals in mice balb/c; Efeito da vincristina na biodistribuicao dos radiofarmacos pertecnetato de sodio e fitato marcados com Tecnecio-99m em camundongos balb/c. Brazil: N. p., 1997. Web.
Britto, Deise M.M., Souza Freitas, Rosemeire de, Paula, Emilio F. de, & Bernardo-Filho, Mario. Effect of vincristine on biodistribution of sodium pertechnetate and 99 m Tc-phytate radiopharmaceuticals in mice balb/c; Efeito da vincristina na biodistribuicao dos radiofarmacos pertecnetato de sodio e fitato marcados com Tecnecio-99m em camundongos balb/c. Brazil.
Britto, Deise M.M., Souza Freitas, Rosemeire de, Paula, Emilio F. de, and Bernardo-Filho, Mario. 1997. "Effect of vincristine on biodistribution of sodium pertechnetate and 99 m Tc-phytate radiopharmaceuticals in mice balb/c; Efeito da vincristina na biodistribuicao dos radiofarmacos pertecnetato de sodio e fitato marcados com Tecnecio-99m em camundongos balb/c." Brazil.
@misc{etde_545735,
title = {Effect of vincristine on biodistribution of sodium pertechnetate and 99 m Tc-phytate radiopharmaceuticals in mice balb/c; Efeito da vincristina na biodistribuicao dos radiofarmacos pertecnetato de sodio e fitato marcados com Tecnecio-99m em camundongos balb/c}
author = {Britto, Deise M.M., Souza Freitas, Rosemeire de, Paula, Emilio F. de, and Bernardo-Filho, Mario}
abstractNote = {Vincristine is a drug used in chemotherapy for cancer treatment. The radiopharmaceuticals biodistribution or pharmacokinetics can be modify by drugs effect, diseases, surgery and radiotherapy. The absence of knowledge of these factors may result in an unexpected behavior of the radiopharmaceuticals. In this work was studied the effect of vincristine on biodistribution of pertechnetate used for thyroid and brain scintigraphy and 99 mTc-phytate used for hepatic scintigraphy. 5 refs., 5 tabs.}
place = {Brazil}
year = {1997}
month = {Dec}
}