Abstract
Thermally reversible hydrogels were synthesized by radiation-induced copolymerization of acryloyl-Lpropine methyl ester with hydrophilic or hydrophobic monomers. The preparation of this copolymers has the purpose to obtain materials for biomedicalk application as drug delivery systems. Acetaminophen, an analgesic and antipyretic drug, was entrapped into some thermoresponsive hydrogels. It was found that the release profiles of drug can be controlled by copolymer porosity, hydrophilicity and changing the environmental temperature. (author). 4 refs., 3 figs.
Martellini, Flavia;
Higa, Olga Z;
[1]
Yoshida, Masaru;
[2]
Katakai, Ryoichi;
[3]
Carenza, Mario
[4]
- Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)
- Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment. Dept. of Material Development
- Gunma Univ., Kiryu (Japan). Faculty of Engineering. Dept. of Chemistry
- Istituto di Fotochimica Radiazioni d`Alta Energia, Legnaro, Padova (Italy)
Citation Formats
Martellini, Flavia, Higa, Olga Z, Yoshida, Masaru, Katakai, Ryoichi, and Carenza, Mario.
Radiation synthesis of hydrogels for biomedical applications.
Brazil: N. p.,
1997.
Web.
Martellini, Flavia, Higa, Olga Z, Yoshida, Masaru, Katakai, Ryoichi, & Carenza, Mario.
Radiation synthesis of hydrogels for biomedical applications.
Brazil.
Martellini, Flavia, Higa, Olga Z, Yoshida, Masaru, Katakai, Ryoichi, and Carenza, Mario.
1997.
"Radiation synthesis of hydrogels for biomedical applications."
Brazil.
@misc{etde_545351,
title = {Radiation synthesis of hydrogels for biomedical applications}
author = {Martellini, Flavia, Higa, Olga Z, Yoshida, Masaru, Katakai, Ryoichi, and Carenza, Mario}
abstractNote = {Thermally reversible hydrogels were synthesized by radiation-induced copolymerization of acryloyl-Lpropine methyl ester with hydrophilic or hydrophobic monomers. The preparation of this copolymers has the purpose to obtain materials for biomedicalk application as drug delivery systems. Acetaminophen, an analgesic and antipyretic drug, was entrapped into some thermoresponsive hydrogels. It was found that the release profiles of drug can be controlled by copolymer porosity, hydrophilicity and changing the environmental temperature. (author). 4 refs., 3 figs.}
place = {Brazil}
year = {1997}
month = {Dec}
}
title = {Radiation synthesis of hydrogels for biomedical applications}
author = {Martellini, Flavia, Higa, Olga Z, Yoshida, Masaru, Katakai, Ryoichi, and Carenza, Mario}
abstractNote = {Thermally reversible hydrogels were synthesized by radiation-induced copolymerization of acryloyl-Lpropine methyl ester with hydrophilic or hydrophobic monomers. The preparation of this copolymers has the purpose to obtain materials for biomedicalk application as drug delivery systems. Acetaminophen, an analgesic and antipyretic drug, was entrapped into some thermoresponsive hydrogels. It was found that the release profiles of drug can be controlled by copolymer porosity, hydrophilicity and changing the environmental temperature. (author). 4 refs., 3 figs.}
place = {Brazil}
year = {1997}
month = {Dec}
}