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Importance of radioimmunoassay of insulin secretion disorder as atherogenic factor

Abstract

Using a radioimmunoassay a C-peptide levei was revealed in children, pregnant and lying-in women as well as in patients with insulin-dependent diabetes mellitus. After breakfast and insulin administration wich curative purposes the IRI concentration in children increased whereas the C-peptide level changed insignificantly. Changes of the insulin secretion were more noticeable in severe diabetes mejlitus with vascular complications and in disease decompensation. The atherogenic nature of the lipid metaboiism (an increase in the cholesterol, triglyceride and ..beta..-lipoprotein levels), changes in the liver and tendency to vascular involvement are results of insulin effect inadequacy. Such metabolic derangements in pregnant women create unfavorable conditions for the development of fetus and may lead to early atherogenic processes.
Publication Date:
Nov 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-057943; EDB-85-141794
Resource Relation:
Journal Name: Med. Radiol.; (USSR); Journal Volume: 29:11
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; INSULIN; RADIOIMMUNOASSAY; PEPTIDES; BLOOD CHEMISTRY; BLOOD SERUM; CHILDREN; DIABETES MELLITUS; FETUSES; LIPIDS; METABOLISM; PARTURITION; PATIENTS; PREGNANCY; SECRETION; WOMEN; AGE GROUPS; ANIMALS; DISEASES; ENDOCRINE DISEASES; FEMALES; HORMONES; ISOTOPE APPLICATIONS; MAMMALS; MAN; METABOLIC DISEASES; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PRIMATES; PROTEINS; RADIOASSAY; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5446351
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: MERAA
Submitting Site:
HEDB
Size:
Pages: 37-40
Announcement Date:
Aug 01, 1985

Citation Formats

Knyazev, Yu A, Bespalova, V A, Vakhrusheva, L L, Kirbasova, N P, and Severtseva, V V. Importance of radioimmunoassay of insulin secretion disorder as atherogenic factor. USSR: N. p., 1984. Web.
Knyazev, Yu A, Bespalova, V A, Vakhrusheva, L L, Kirbasova, N P, & Severtseva, V V. Importance of radioimmunoassay of insulin secretion disorder as atherogenic factor. USSR.
Knyazev, Yu A, Bespalova, V A, Vakhrusheva, L L, Kirbasova, N P, and Severtseva, V V. 1984. "Importance of radioimmunoassay of insulin secretion disorder as atherogenic factor." USSR.
@misc{etde_5446351,
title = {Importance of radioimmunoassay of insulin secretion disorder as atherogenic factor}
author = {Knyazev, Yu A, Bespalova, V A, Vakhrusheva, L L, Kirbasova, N P, and Severtseva, V V}
abstractNote = {Using a radioimmunoassay a C-peptide levei was revealed in children, pregnant and lying-in women as well as in patients with insulin-dependent diabetes mellitus. After breakfast and insulin administration wich curative purposes the IRI concentration in children increased whereas the C-peptide level changed insignificantly. Changes of the insulin secretion were more noticeable in severe diabetes mejlitus with vascular complications and in disease decompensation. The atherogenic nature of the lipid metaboiism (an increase in the cholesterol, triglyceride and ..beta..-lipoprotein levels), changes in the liver and tendency to vascular involvement are results of insulin effect inadequacy. Such metabolic derangements in pregnant women create unfavorable conditions for the development of fetus and may lead to early atherogenic processes.}
journal = []
volume = {29:11}
journal type = {AC}
place = {USSR}
year = {1984}
month = {Nov}
}