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Osteoarthropathy in dialysis amyloidosis; Radiological and clinical findings. Aspetti radiologici e clinici dell'amiloidosi osteoarticolare da dialisi

Abstract

Many long-term (>60 months) hemodialysis patients develop a severe osteoarticular disease, called 'dialysis arthropathy', which is characterized by the deposition in bone and synovia of a new type of amyloid made mainly of {beta}{sub 2}-microglobulin. In the present study, 31 patients (17 males, 14 females; age 54.1{+-}13 years) undergoing chronic hemodialysis arthropathy by means of clinics and of radiological investigations (conventional radiography and computed tomography). Sixteen patients (51.6%) had radiographic evidence of dialysis arthropathy: geodes (shoulders, 12 cases; wrists, 11; hips, 2; knees, 2) and/or destructive arthropathies (cervical spine, 13 cases; dorsolumbar spine, 2; hands, 2; hips, 1). Within 24 months, these lesions were found to progress slowly in the majoriry of cases. In the diagnostic process, CT should be employed in the study of spine, shoulders and hips when the lesions have not been sufficiently demonstrated by conventional radiography in the presence of evident clinical signs. Patients with dialysis arthropathy had undergone dialysis for longer periods than those without it (p<0.005) and showed a significantly higher incidence of both carpal tunnel syndrome (p<0.0005) and shoulder pain (p<0.005). Our findings confirm the high incidence and clinical importance of dialysis arthropathy in long-term hemodialysis patients end the value of diagnostic imaging  More>>
Authors:
Baldrati, L; Feletti, C; Capponcini, C; Docci, D; [1]  Rocchi, A; Balbi, B; Bonsanto, R; Mughetti, M; [2]  Pasini, A [3] 
  1. Ospedale M. Bufalini, Cesena (Italy). Serv. di Radiologia
  2. Ospedale M. Bufalini, Cesena (Italy). Serv. di Nefrologia e Dialisi
  3. Ospedale M. Bufalini, Cesena (Italy) Serv. di Neuroradiologia
Publication Date:
Jan 01, 1991
Product Type:
Journal Article
Reference Number:
AIX-23-035754; EDB-92-082438
Resource Relation:
Journal Name: Radiologia Medica; (Italy); Journal Volume: 81:6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARMS; BIOMEDICAL RADIOGRAPHY; COMPUTERIZED TOMOGRAPHY; BONE JOINTS; DIALYSIS; GLOBULINS-BETA; HEMIC DISEASES; PATIENTS; RHEUMATIC DISEASES; BODY; BODY AREAS; DIAGNOSTIC TECHNIQUES; DISEASES; GLOBULINS; LIMBS; MEDICINE; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOLOGY; SEPARATION PROCESSES; SKELETAL DISEASES; SKELETON; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5443596
Country of Origin:
Italy
Language:
Italian
Other Identifying Numbers:
Journal ID: ISSN 0033-8362; CODEN: RAMEA
Submitting Site:
INIS
Size:
Pages: 818-821
Announcement Date:
Jun 01, 1992

Citation Formats

Baldrati, L, Feletti, C, Capponcini, C, Docci, D, Rocchi, A, Balbi, B, Bonsanto, R, Mughetti, M, and Pasini, A. Osteoarthropathy in dialysis amyloidosis; Radiological and clinical findings. Aspetti radiologici e clinici dell'amiloidosi osteoarticolare da dialisi. Italy: N. p., 1991. Web.
Baldrati, L, Feletti, C, Capponcini, C, Docci, D, Rocchi, A, Balbi, B, Bonsanto, R, Mughetti, M, &amp; Pasini, A. Osteoarthropathy in dialysis amyloidosis; Radiological and clinical findings. Aspetti radiologici e clinici dell'amiloidosi osteoarticolare da dialisi. Italy.
Baldrati, L, Feletti, C, Capponcini, C, Docci, D, Rocchi, A, Balbi, B, Bonsanto, R, Mughetti, M, and Pasini, A. 1991. "Osteoarthropathy in dialysis amyloidosis; Radiological and clinical findings. Aspetti radiologici e clinici dell'amiloidosi osteoarticolare da dialisi." Italy.
@misc{etde_5443596,
title = {Osteoarthropathy in dialysis amyloidosis; Radiological and clinical findings. Aspetti radiologici e clinici dell'amiloidosi osteoarticolare da dialisi}
author = {Baldrati, L, Feletti, C, Capponcini, C, Docci, D, Rocchi, A, Balbi, B, Bonsanto, R, Mughetti, M, and Pasini, A}
abstractNote = {Many long-term (>60 months) hemodialysis patients develop a severe osteoarticular disease, called 'dialysis arthropathy', which is characterized by the deposition in bone and synovia of a new type of amyloid made mainly of {beta}{sub 2}-microglobulin. In the present study, 31 patients (17 males, 14 females; age 54.1{+-}13 years) undergoing chronic hemodialysis arthropathy by means of clinics and of radiological investigations (conventional radiography and computed tomography). Sixteen patients (51.6%) had radiographic evidence of dialysis arthropathy: geodes (shoulders, 12 cases; wrists, 11; hips, 2; knees, 2) and/or destructive arthropathies (cervical spine, 13 cases; dorsolumbar spine, 2; hands, 2; hips, 1). Within 24 months, these lesions were found to progress slowly in the majoriry of cases. In the diagnostic process, CT should be employed in the study of spine, shoulders and hips when the lesions have not been sufficiently demonstrated by conventional radiography in the presence of evident clinical signs. Patients with dialysis arthropathy had undergone dialysis for longer periods than those without it (p<0.005) and showed a significantly higher incidence of both carpal tunnel syndrome (p<0.0005) and shoulder pain (p<0.005). Our findings confirm the high incidence and clinical importance of dialysis arthropathy in long-term hemodialysis patients end the value of diagnostic imaging in screening such patients for those lesions.}
journal = []
volume = {81:6}
journal type = {AC}
place = {Italy}
year = {1991}
month = {Jan}
}