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Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study

Abstract

Results from neuropsychological tests, collected under double-blind-precautions, were evaluated for 115 schoolage children (mean age: 9.4 years) living in a lead smelter area (Stolberg, FRG). Tooth-lead concentrations (PbT) from shed incisor teeth as measures of longtime lead-exposure were available for these children (mean . 6.16 ppm; range: 1.9-38.5 ppm), and for 83 of them blood-lead concentrations (PbB) were available as well (mean . 14.3 micrograms/dl; range: 6.8-33.8 micrograms/dl). The following functional capacities were tested: intelligence (German WISC), perceptual-motor integration (Goettinger Formreproduktionstest . GFT, Diagnosticum for Cerebralschaedigung . DCS), reaction performance (Wiener Determinationsgeraet), finger-wrist tapping-speed, and repetitive cancellation-performance (Differentieller Leistungstest). In addition standardized behavior ratings were obtained by the examiners, the mothers, and the teachers. Multiple stepwise regression-analysis (forced solution) was calculated for outcome-variables and Pb-tooth, including age, sex, duration of labor, and socio-hereditary background as covariates. The results are discussed within the framework of attention-deficit disorder, and compared to neurobehavioral Pb-effects from animal-experiments, which provide suggestive evidence for a causal relationship between developmental lead-exposure and certain neurobehavioral deficits.
Publication Date:
Jan 01, 1983
Product Type:
Journal Article
Reference Number:
EDB-84-032322
Resource Relation:
Journal Name: Int. Arch. Occup. Environ. Health; (Germany, Federal Republic of); Journal Volume: 51:3
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CHILDREN; BEHAVIOR; MENTAL DISORDERS; LEAD; BIOLOGICAL EFFECTS; BLOOD; REFLEXES; TEETH; TOXICITY; AGE GROUPS; BIOLOGICAL MATERIALS; BODY FLUIDS; DIGESTIVE SYSTEM; ELEMENTS; MATERIALS; METALS; ORAL CAVITY; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
OSTI ID:
5425427
Research Organizations:
Medizinisches Institut fuer Umwelthygiene an der Universitaet Duesseldorf, Federal Republic of Germany
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: IAEHD
Submitting Site:
HEDB
Size:
Pages: 231-252
Announcement Date:
Aug 01, 1983

Citation Formats

Winneke, G, Kraemer, U, Brockhaus, A, Ewers, U, Kujanek, G, Lechner, H, and Janke, W. Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study. Germany: N. p., 1983. Web. doi:10.1007/BF00377755.
Winneke, G, Kraemer, U, Brockhaus, A, Ewers, U, Kujanek, G, Lechner, H, & Janke, W. Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study. Germany. https://doi.org/10.1007/BF00377755
Winneke, G, Kraemer, U, Brockhaus, A, Ewers, U, Kujanek, G, Lechner, H, and Janke, W. 1983. "Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study." Germany. https://doi.org/10.1007/BF00377755.
@misc{etde_5425427,
title = {Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study}
author = {Winneke, G, Kraemer, U, Brockhaus, A, Ewers, U, Kujanek, G, Lechner, H, and Janke, W}
abstractNote = {Results from neuropsychological tests, collected under double-blind-precautions, were evaluated for 115 schoolage children (mean age: 9.4 years) living in a lead smelter area (Stolberg, FRG). Tooth-lead concentrations (PbT) from shed incisor teeth as measures of longtime lead-exposure were available for these children (mean . 6.16 ppm; range: 1.9-38.5 ppm), and for 83 of them blood-lead concentrations (PbB) were available as well (mean . 14.3 micrograms/dl; range: 6.8-33.8 micrograms/dl). The following functional capacities were tested: intelligence (German WISC), perceptual-motor integration (Goettinger Formreproduktionstest . GFT, Diagnosticum for Cerebralschaedigung . DCS), reaction performance (Wiener Determinationsgeraet), finger-wrist tapping-speed, and repetitive cancellation-performance (Differentieller Leistungstest). In addition standardized behavior ratings were obtained by the examiners, the mothers, and the teachers. Multiple stepwise regression-analysis (forced solution) was calculated for outcome-variables and Pb-tooth, including age, sex, duration of labor, and socio-hereditary background as covariates. The results are discussed within the framework of attention-deficit disorder, and compared to neurobehavioral Pb-effects from animal-experiments, which provide suggestive evidence for a causal relationship between developmental lead-exposure and certain neurobehavioral deficits.}
doi = {10.1007/BF00377755}
journal = []
volume = {51:3}
journal type = {AC}
place = {Germany}
year = {1983}
month = {Jan}
}