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Radioimmunoassay for human plasma 8-arginine-vasopressin

Journal Article:

Abstract

A radioimmunoassay for human plasma vasopressin (AVP) which permits the estimation of antidiuretic hormone (ADH) level as low as 0.8pg/ml, was developed. The average plasma level of AVP after overnight water restriction was found to be 14.3pg/ml (sd=4.4pg/ml) in normal subjects. They provoked a hypersecretion of ADH by the intravenous injection of 1-2mg of nicotine. In 11 volunteer normal subjects this stimulation by nicotine provoked ADH hypersecretion which reached a maximum between 2nd and 15th minutes after injection. In 3 cases of diabetes insipidus, nicotine injection did not induce ADH hypersecretion: in 1 case of potomania this response was weak; in 2 cases of syndrome of inappropriate ADH secretion, AVP plasma levels were elevated and the response after nicotine stimulation was exaggerated.
Authors:
Conte-Devolx, B; [1]  Rougon-Rapuzzi, G; [2]  Millet, Y [3] 
  1. Hopital de la Conception, 13 - Marseille (France)
  2. Centre National de la Recherche Scientifique, 13 - Marseille (France)
  3. Aix-Marseille-2 Univ., 13 - Marseille (France)
Publication Date:
Jan 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-08-330536; EDB-78-028516
Resource Relation:
Journal Name: Ann. Endocrinol. (Paris); (France); Journal Volume: 38:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; VASOPRESSIN; RADIOIMMUNOASSAY; BLOOD PLASMA; NICOTINE; ALKALOIDS; AMINES; AZINES; AZOLES; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; HETEROCYCLIC COMPOUNDS; HORMONES; ISOTOPE APPLICATIONS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PEPTIDE HORMONES; PITUITARY HORMONES; PYRIDINES; PYRROLES; PYRROLIDINES; RADIOASSAY; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5402042
Country of Origin:
France
Language:
French
Other Identifying Numbers:
Journal ID: CODEN: ANENA
Submitting Site:
INIS
Size:
Pages: 61-72
Announcement Date:
Dec 01, 1977

Journal Article:

Citation Formats

Conte-Devolx, B, Rougon-Rapuzzi, G, and Millet, Y. Radioimmunoassay for human plasma 8-arginine-vasopressin. France: N. p., 1977. Web.
Conte-Devolx, B, Rougon-Rapuzzi, G, & Millet, Y. Radioimmunoassay for human plasma 8-arginine-vasopressin. France.
Conte-Devolx, B, Rougon-Rapuzzi, G, and Millet, Y. 1977. "Radioimmunoassay for human plasma 8-arginine-vasopressin." France.
@misc{etde_5402042,
title = {Radioimmunoassay for human plasma 8-arginine-vasopressin}
author = {Conte-Devolx, B, Rougon-Rapuzzi, G, and Millet, Y}
abstractNote = {A radioimmunoassay for human plasma vasopressin (AVP) which permits the estimation of antidiuretic hormone (ADH) level as low as 0.8pg/ml, was developed. The average plasma level of AVP after overnight water restriction was found to be 14.3pg/ml (sd=4.4pg/ml) in normal subjects. They provoked a hypersecretion of ADH by the intravenous injection of 1-2mg of nicotine. In 11 volunteer normal subjects this stimulation by nicotine provoked ADH hypersecretion which reached a maximum between 2nd and 15th minutes after injection. In 3 cases of diabetes insipidus, nicotine injection did not induce ADH hypersecretion: in 1 case of potomania this response was weak; in 2 cases of syndrome of inappropriate ADH secretion, AVP plasma levels were elevated and the response after nicotine stimulation was exaggerated.}
journal = {Ann. Endocrinol. (Paris); (France)}
volume = {38:1}
journal type = {AC}
place = {France}
year = {1977}
month = {Jan}
}