Abstract
The role of calcium ions in regulating the structure and function of non-muscle cells is a subject of intense study. Several lines of evidence that calcium may be essential in the function of polymorphonuclear leuocytes (PMNL) and an important control element in the process of phagocytosis. Direct studies of calcium distribution and fluxes have only recently been undertaken. To our knowledge, no report of calcium movements during normal phagocytosis has been published. In the context of an overall study of calcium dynamics in the PMNL, we report here initial studies on /sup 45/Ca efflux in prelabelled guinea pig PMNL. The results demonstrate the energy-dependence of resting calcium efflux and an increased efflux upon addition of phagocytic particles which is not dependent on particle internalization.
Barthelemy, A;
Schell-Frederick, E;
[1]
Paridaens, R
[2]
- Brussels Univ. (Belgium). Institut de Recherche Interdisciplinaire
- Brussels Univ. (Belgium). Faculte de Medicine
Citation Formats
Barthelemy, A, Schell-Frederick, E, and Paridaens, R.
Phagocytosis-induced /sup 45/calcium efflux in polymorphonuclear leucocytes.
Netherlands: N. p.,
1977.
Web.
Barthelemy, A, Schell-Frederick, E, & Paridaens, R.
Phagocytosis-induced /sup 45/calcium efflux in polymorphonuclear leucocytes.
Netherlands.
Barthelemy, A, Schell-Frederick, E, and Paridaens, R.
1977.
"Phagocytosis-induced /sup 45/calcium efflux in polymorphonuclear leucocytes."
Netherlands.
@misc{etde_5371369,
title = {Phagocytosis-induced /sup 45/calcium efflux in polymorphonuclear leucocytes}
author = {Barthelemy, A, Schell-Frederick, E, and Paridaens, R}
abstractNote = {The role of calcium ions in regulating the structure and function of non-muscle cells is a subject of intense study. Several lines of evidence that calcium may be essential in the function of polymorphonuclear leuocytes (PMNL) and an important control element in the process of phagocytosis. Direct studies of calcium distribution and fluxes have only recently been undertaken. To our knowledge, no report of calcium movements during normal phagocytosis has been published. In the context of an overall study of calcium dynamics in the PMNL, we report here initial studies on /sup 45/Ca efflux in prelabelled guinea pig PMNL. The results demonstrate the energy-dependence of resting calcium efflux and an increased efflux upon addition of phagocytic particles which is not dependent on particle internalization.}
journal = []
volume = {82:2}
journal type = {AC}
place = {Netherlands}
year = {1977}
month = {Oct}
}
title = {Phagocytosis-induced /sup 45/calcium efflux in polymorphonuclear leucocytes}
author = {Barthelemy, A, Schell-Frederick, E, and Paridaens, R}
abstractNote = {The role of calcium ions in regulating the structure and function of non-muscle cells is a subject of intense study. Several lines of evidence that calcium may be essential in the function of polymorphonuclear leuocytes (PMNL) and an important control element in the process of phagocytosis. Direct studies of calcium distribution and fluxes have only recently been undertaken. To our knowledge, no report of calcium movements during normal phagocytosis has been published. In the context of an overall study of calcium dynamics in the PMNL, we report here initial studies on /sup 45/Ca efflux in prelabelled guinea pig PMNL. The results demonstrate the energy-dependence of resting calcium efflux and an increased efflux upon addition of phagocytic particles which is not dependent on particle internalization.}
journal = []
volume = {82:2}
journal type = {AC}
place = {Netherlands}
year = {1977}
month = {Oct}
}