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Malignant lymphoma in central nervous system (CNS). Report of a case with characteristic CT finding and amnesia

Abstract

A 71-year-old male was admitted to Kohka Public Hospital on January 4, 1980, because of frequent vomiting and recent memory loss. Two weeks before admission upper G-I series showed no abnormalities. Physical and neurological examinations revealed no abnormalities except for slightly apathetic appearance and recent memory loss. Mild pleocytosis and marked increase of protein in CSF were observed. CT scan on January 17 showed high density areas in both medial sides of temporal lobes with remarkable contrast enhancement. His memory and, consciousness disturbances gradually aggravated, accompanied by abnormal density spreading around the ventricle walls like ventriculitis. He was transfered to Kyoto University Hospital on March 17, and malignant lymphoma was diagnosed on the basis of CSF cytology. Radiation and chemotherapy alleviated the CNS involvement and he regained normal mental function. On June 16, he developed pneumonia followed by status epilepticus. Autopsy findings revealed no lymphoid cell infiltration, but fibrous tissues in both hippocampal gyri and lymphomatous cells in the liver, which could not be suspected on clinical examinations. Apparent malignant lymphoma cells were not found in lymph nodes. This case indicated peculiar evolution of malignant lymphoma from liver to CNS or vice versa. We could not decide which organ was  More>>
Authors:
Fujiyoshi, Kenji; Fukuyama, Hidenao; Akiguchi, Ichiro; Kameyama, Masakuni; [1]  Nishimura, Toshio
  1. Kyoto Univ. (Japan). Faculty of Medicine
Publication Date:
Jul 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-16-054123; EDB-85-134734
Resource Relation:
Journal Name: Shinkei Naika; (Japan); Journal Volume: 21:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; CAT SCANNING; LYMPHOMAS; DIAGNOSIS; AUTOPSY; IMAGES; NERVOUS SYSTEM DISEASES; PATIENTS; BODY; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; NEOPLASMS; NERVOUS SYSTEM; ORGANS; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5368865
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: SNAID
Submitting Site:
HEDB
Size:
Pages: 31-37
Announcement Date:
Jul 01, 1985

Citation Formats

Fujiyoshi, Kenji, Fukuyama, Hidenao, Akiguchi, Ichiro, Kameyama, Masakuni, and Nishimura, Toshio. Malignant lymphoma in central nervous system (CNS). Report of a case with characteristic CT finding and amnesia. Japan: N. p., 1984. Web.
Fujiyoshi, Kenji, Fukuyama, Hidenao, Akiguchi, Ichiro, Kameyama, Masakuni, & Nishimura, Toshio. Malignant lymphoma in central nervous system (CNS). Report of a case with characteristic CT finding and amnesia. Japan.
Fujiyoshi, Kenji, Fukuyama, Hidenao, Akiguchi, Ichiro, Kameyama, Masakuni, and Nishimura, Toshio. 1984. "Malignant lymphoma in central nervous system (CNS). Report of a case with characteristic CT finding and amnesia." Japan.
@misc{etde_5368865,
title = {Malignant lymphoma in central nervous system (CNS). Report of a case with characteristic CT finding and amnesia}
author = {Fujiyoshi, Kenji, Fukuyama, Hidenao, Akiguchi, Ichiro, Kameyama, Masakuni, and Nishimura, Toshio}
abstractNote = {A 71-year-old male was admitted to Kohka Public Hospital on January 4, 1980, because of frequent vomiting and recent memory loss. Two weeks before admission upper G-I series showed no abnormalities. Physical and neurological examinations revealed no abnormalities except for slightly apathetic appearance and recent memory loss. Mild pleocytosis and marked increase of protein in CSF were observed. CT scan on January 17 showed high density areas in both medial sides of temporal lobes with remarkable contrast enhancement. His memory and, consciousness disturbances gradually aggravated, accompanied by abnormal density spreading around the ventricle walls like ventriculitis. He was transfered to Kyoto University Hospital on March 17, and malignant lymphoma was diagnosed on the basis of CSF cytology. Radiation and chemotherapy alleviated the CNS involvement and he regained normal mental function. On June 16, he developed pneumonia followed by status epilepticus. Autopsy findings revealed no lymphoid cell infiltration, but fibrous tissues in both hippocampal gyri and lymphomatous cells in the liver, which could not be suspected on clinical examinations. Apparent malignant lymphoma cells were not found in lymph nodes. This case indicated peculiar evolution of malignant lymphoma from liver to CNS or vice versa. We could not decide which organ was primary. CT findings of this case was very interesting; they resembled ventriculitis, which simulate tumors such as medulloblastoma or ependymoma spreading under ependymal lining.}
journal = []
volume = {21:1}
journal type = {AC}
place = {Japan}
year = {1984}
month = {Jul}
}