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Role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer

Abstract

In order to evaluate the role of CT scan and bone scan in staging patients with non-small-cell lung cancer presumably indicated for surgery, 70 consecutive patients who underwent thoracotomy were reviewed. Most of them received mediastinal and multi-organ (brain, liver and adrenal) CT scans and a bone scan. In the most recent 40 of the 70 patients, CT findings of the mediastinal lymph nodes were compared to the pathology following complete sampling. The overall accuracy of the mediastinal CT was 60.0 per cent (12 true positive and 12 true negative), but the negative predictable value was 12/(12 + 3) or 80.0 per cent, whereas 3 were false negatives though they showed an acceptable postoperative course. Sixteen out of 21 patients with one, or at the most, three enlarged nodes detected on CT also did well postoperatively and retrospectively, were considered not to have required mediastinoscopy. A group of patients showing no, or at the most, three enlarged mediastinal lymph nodes on CT may be considered as candidates for surgery even without mediastinoscopy. Multi-organ survey by means of CT was believed cost-ineffective and omittable. Bone scan however, retrospectively detected three true positives among 20 patients with a positive uptake, so that  More>>
Publication Date:
Sep 01, 1987
Product Type:
Journal Article
Reference Number:
JPN-88-061536; EDB-88-068583
Resource Relation:
Journal Name: Jpn. J. Surg.; (Japan); Journal Volume: 17:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; CARCINOMAS; CAT SCANNING; ACCURACY; ADRENAL GLANDS; BIOPSY; BRAIN; LIVER; LYMPH NODES; MEDIASTINUM; METASTASES; SCINTISCANNING; SENSITIVITY; SKELETON; SPECIFICITY; SURGERY; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; BODY AREAS; CENTRAL NERVOUS SYSTEM; CHEST; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; ENDOCRINE GLANDS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LYMPHATIC SYSTEM; MEDICINE; NEOPLASMS; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5360991
Research Organizations:
St. Marianna University, School of Medicine, Kawasaki, Japan
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JJSGA
Submitting Site:
JPN
Size:
Pages: 362-368
Announcement Date:
Mar 01, 1988

Citation Formats

Osada, Hiroaki, Nakajima, Yasuo, Taira, Yasuhiko, Yokote, Kumio, and Noguchi, Teruhiko. Role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer. Japan: N. p., 1987. Web.
Osada, Hiroaki, Nakajima, Yasuo, Taira, Yasuhiko, Yokote, Kumio, & Noguchi, Teruhiko. Role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer. Japan.
Osada, Hiroaki, Nakajima, Yasuo, Taira, Yasuhiko, Yokote, Kumio, and Noguchi, Teruhiko. 1987. "Role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer." Japan.
@misc{etde_5360991,
title = {Role of mediastinal and multi-organ CT scans in staging presumable surgical candidates with non-small-cell lung cancer}
author = {Osada, Hiroaki, Nakajima, Yasuo, Taira, Yasuhiko, Yokote, Kumio, and Noguchi, Teruhiko}
abstractNote = {In order to evaluate the role of CT scan and bone scan in staging patients with non-small-cell lung cancer presumably indicated for surgery, 70 consecutive patients who underwent thoracotomy were reviewed. Most of them received mediastinal and multi-organ (brain, liver and adrenal) CT scans and a bone scan. In the most recent 40 of the 70 patients, CT findings of the mediastinal lymph nodes were compared to the pathology following complete sampling. The overall accuracy of the mediastinal CT was 60.0 per cent (12 true positive and 12 true negative), but the negative predictable value was 12/(12 + 3) or 80.0 per cent, whereas 3 were false negatives though they showed an acceptable postoperative course. Sixteen out of 21 patients with one, or at the most, three enlarged nodes detected on CT also did well postoperatively and retrospectively, were considered not to have required mediastinoscopy. A group of patients showing no, or at the most, three enlarged mediastinal lymph nodes on CT may be considered as candidates for surgery even without mediastinoscopy. Multi-organ survey by means of CT was believed cost-ineffective and omittable. Bone scan however, retrospectively detected three true positives among 20 patients with a positive uptake, so that it cannot be omitted out of hand, though further examination of this point is required.}
journal = []
volume = {17:5}
journal type = {AC}
place = {Japan}
year = {1987}
month = {Sep}
}