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FDG-PET in the diagnosis of neuropsychiatric Lupus erythematosus and comparison with computed tomography and magnetic resonance imaging. Einsatz der FDG-PET bei der Diagnostik des zentralnervoesen Lupus erythematodes und Vergleich mit CT und MRI

Journal Article:

Abstract

Central nervous system involvement has been found in 30-75% of all cases of systemic lupus erythematosus (SLE). Up to now, clinical diagnosis is difficult and there are no markers for disease activity. We have compared cranial computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodesoxyglucose (FDG) in two cases. FDG-PET is shown to be the most sensitive method demonstrating even reversible deficits and a better correlation with other neurological findings. MRI seems to be more sensitive than CT. A survey of the literature concerning imaging methods in neuropsychiatric SLE is given. The special problem of neuronal desactivation by antineuronal activity is discussed. (orig.).
Authors:
Stoppe, G; [1]  Wildhagen, K; [2]  Meyer, G J; [3]  Schober, O [4] 
  1. Medizinische Hochschule Hannover (Germany, F.R.). Neurologische Klinik mit Klinischer Neurophysiologie
  2. Medizinische Hochschule Hannover (Germany, F.R.). Abt. Immunologie und Transfusionsmedizin
  3. Medizinische Hochschule Hannover (Germany, F.R.). Abt. Nuklearmedizin und Spezielle Biophysik
  4. Muenster Univ. (Germany, F.R.). Klinik und Poliklinik fuer Nuklearmedizin
Publication Date:
Oct 01, 1989
Product Type:
Journal Article
Reference Number:
DEN-89-014732; EDB-90-011251
Resource Relation:
Journal Name: Nuklearmedizin (Stuttgart); (F.R. Germany); Journal Volume: 28:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; LUPUS; POSITRON COMPUTED TOMOGRAPHY; NERVOUS SYSTEM DISEASES; DIAGNOSIS; COMPUTERIZED TOMOGRAPHY; FLUORINE 18; FLUORODEOXYGLUCOSE; IMAGES; NMR IMAGING; PATIENTS; RADIOPHARMACEUTICALS; ANTIMETABOLITES; BACTERIAL DISEASES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; IMMUNE SYSTEM DISEASES; INFECTIOUS DISEASES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; SKIN DISEASES; TOMOGRAPHY; TUBERCULOSIS; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550602 - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5358559
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: ISSN 0029-5566; CODEN: NUKLD
Submitting Site:
DEN
Size:
Pages: 187-192
Announcement Date:
Jan 15, 1990

Journal Article:

Citation Formats

Stoppe, G, Wildhagen, K, Meyer, G J, and Schober, O. FDG-PET in the diagnosis of neuropsychiatric Lupus erythematosus and comparison with computed tomography and magnetic resonance imaging. Einsatz der FDG-PET bei der Diagnostik des zentralnervoesen Lupus erythematodes und Vergleich mit CT und MRI. Germany: N. p., 1989. Web.
Stoppe, G, Wildhagen, K, Meyer, G J, & Schober, O. FDG-PET in the diagnosis of neuropsychiatric Lupus erythematosus and comparison with computed tomography and magnetic resonance imaging. Einsatz der FDG-PET bei der Diagnostik des zentralnervoesen Lupus erythematodes und Vergleich mit CT und MRI. Germany.
Stoppe, G, Wildhagen, K, Meyer, G J, and Schober, O. 1989. "FDG-PET in the diagnosis of neuropsychiatric Lupus erythematosus and comparison with computed tomography and magnetic resonance imaging. Einsatz der FDG-PET bei der Diagnostik des zentralnervoesen Lupus erythematodes und Vergleich mit CT und MRI." Germany.
@misc{etde_5358559,
title = {FDG-PET in the diagnosis of neuropsychiatric Lupus erythematosus and comparison with computed tomography and magnetic resonance imaging. Einsatz der FDG-PET bei der Diagnostik des zentralnervoesen Lupus erythematodes und Vergleich mit CT und MRI}
author = {Stoppe, G, Wildhagen, K, Meyer, G J, and Schober, O}
abstractNote = {Central nervous system involvement has been found in 30-75% of all cases of systemic lupus erythematosus (SLE). Up to now, clinical diagnosis is difficult and there are no markers for disease activity. We have compared cranial computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodesoxyglucose (FDG) in two cases. FDG-PET is shown to be the most sensitive method demonstrating even reversible deficits and a better correlation with other neurological findings. MRI seems to be more sensitive than CT. A survey of the literature concerning imaging methods in neuropsychiatric SLE is given. The special problem of neuronal desactivation by antineuronal activity is discussed. (orig.).}
journal = {Nuklearmedizin (Stuttgart); (F.R. Germany)}
volume = {28:5}
journal type = {AC}
place = {Germany}
year = {1989}
month = {Oct}
}