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Total body irradiation and autologus bone marrow transplantation in acute leukemias and non Hodgkin-lymphomas

Journal Article:

Abstract

From january 1984 to may 1986, 31 patients, 15 ANLL, 8 ALL (in remission status) and 8 NHL (6 in remission, 2 in relapse) have been treated with chemo-radiotherapy (cyclophosphamide 60 mg/kg x 2 days + total body irradiation (TBI): 10 Gy/3 fr./3 days with 4 Gy boost testicular dose in ALL) and autologous bone marrow transplantation (BMT). Seventeen patients are alive, 16 in remission: 9 (60%) ANLL, 2 (25%) ALL, 5 (62%) NHL (median 8+ months, follow up 1+ /29+); 2 patients presented interstitial pneumonitis (6.45%). In this series, very good results have been achieved in ANLL, where no relapse was noted, encouraging achievements in NHL, with 4/8 relapse. Advantages and disadvanteges of autologus relative to allogenic BMT, and of conditioning regimen with or without TBI are discussed.
Publication Date:
Jan 01, 1986
Product Type:
Journal Article
Reference Number:
AIX-19-045415; EDB-88-080884
Resource Relation:
Journal Name: Radiol. Med.; (Italy); Journal Volume: 72:12
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BONE MARROW; TRANSPLANTS; WHOLE-BODY IRRADIATION; HODGKINS DISEASE; LEUKEMIA; COBALT 60; RADIOTHERAPY; ANIMAL TISSUES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COBALT ISOTOPES; DISEASES; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; HEMIC DISEASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LYMPHOMAS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RADIOLOGY; THERAPY; TISSUES; YEARS LIVING RADIOISOTOPES; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
5314735
Research Organizations:
Genoa Univ. (Italy). Ist. di Radiologia. Cattedra B; Centro Trapianto Midollo Osseo, Genoa (Italy). Div. di Ematologia
Country of Origin:
Italy
Language:
Italian
Other Identifying Numbers:
Journal ID: CODEN: RAMEA
Submitting Site:
INIS
Size:
Pages: 955-958
Announcement Date:

Journal Article:

Citation Formats

Corvo, R, Franzone, P, Scarpati, D, Congiu, M, and Carella, A. Total body irradiation and autologus bone marrow transplantation in acute leukemias and non Hodgkin-lymphomas. Italy: N. p., 1986. Web.
Corvo, R, Franzone, P, Scarpati, D, Congiu, M, & Carella, A. Total body irradiation and autologus bone marrow transplantation in acute leukemias and non Hodgkin-lymphomas. Italy.
Corvo, R, Franzone, P, Scarpati, D, Congiu, M, and Carella, A. 1986. "Total body irradiation and autologus bone marrow transplantation in acute leukemias and non Hodgkin-lymphomas." Italy.
@misc{etde_5314735,
title = {Total body irradiation and autologus bone marrow transplantation in acute leukemias and non Hodgkin-lymphomas}
author = {Corvo, R, Franzone, P, Scarpati, D, Congiu, M, and Carella, A}
abstractNote = {From january 1984 to may 1986, 31 patients, 15 ANLL, 8 ALL (in remission status) and 8 NHL (6 in remission, 2 in relapse) have been treated with chemo-radiotherapy (cyclophosphamide 60 mg/kg x 2 days + total body irradiation (TBI): 10 Gy/3 fr./3 days with 4 Gy boost testicular dose in ALL) and autologous bone marrow transplantation (BMT). Seventeen patients are alive, 16 in remission: 9 (60%) ANLL, 2 (25%) ALL, 5 (62%) NHL (median 8+ months, follow up 1+ /29+); 2 patients presented interstitial pneumonitis (6.45%). In this series, very good results have been achieved in ANLL, where no relapse was noted, encouraging achievements in NHL, with 4/8 relapse. Advantages and disadvanteges of autologus relative to allogenic BMT, and of conditioning regimen with or without TBI are discussed.}
journal = {Radiol. Med.; (Italy)}
volume = {72:12}
journal type = {AC}
place = {Italy}
year = {1986}
month = {Jan}
}