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Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra

Journal Article:

Abstract

Between 1952 and 1980 about 250 patients with ankylosing spondylitis were treated with /sup 224/Ra at the Orthopaedic University Hospital of Frankfurt/M. In 1970, 119 of them were examined and X-rayed as was another group of 40 patients in 1980. The results of those examined could be compared with a group of 40 patients treated without /sup 224/Ra. Patients with /sup 224/Ra demonstrated a long-lasting period of subjective improvement after the treatment, with reduced consumption of antirheumatoid and analgesic drugs, on the average. Blood examinations show inflammatory activities. Nevertheless, the ankylosing spondylitis proceeded. In the final stages of the disease, neither the clinical aspects nor the X-rays showed any specific changes. We observed no case of malignant bone tumor. Of the 169 examined patients, 22 had a total of 32 children after the treatment with /sup 224/Ra. Among these was a set of twins with cerebral palsy and diabetes insipidus renalis. In conclusion, /sup 224/Ra in ankylosing spondylitis is a recommended treatment without higher risk compared to the common therapy with drugs.
Authors:
Schmitt, E; [1]  Ruckbeil, C; Wick, R R
  1. Universitatsklinik Friedrichsheim, Frankfurt, West Germany
Publication Date:
Jan 01, 1983
Product Type:
Journal Article
Reference Number:
EDB-84-032168
Resource Relation:
Journal Name: Health Phys.; (United Kingdom); Journal Volume: 44:Sup. 1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE TISSUES; BIOLOGICAL RADIATION EFFECTS; LIVER; BIOMEDICAL RADIOGRAPHY; PATIENTS; RADIUM 224; SPONDYLITIS; ALKALINE EARTH ISOTOPES; ALPHA DECAY RADIOISOTOPES; ANIMAL TISSUES; BIOLOGICAL EFFECTS; BODY; CONNECTIVE TISSUE; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; EVEN-EVEN NUCLEI; GLANDS; HEAVY NUCLEI; ISOTOPES; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ORGANS; RADIATION EFFECTS; RADIOISOTOPES; RADIOLOGY; RADIUM ISOTOPES; RHEUMATIC DISEASES; SKELETAL DISEASES; TISSUES; 560161* - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5295096
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: HLTPA
Submitting Site:
HEDB
Size:
Pages: 197-202
Announcement Date:

Journal Article:

Citation Formats

Schmitt, E, Ruckbeil, C, and Wick, R R. Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra. United Kingdom: N. p., 1983. Web.
Schmitt, E, Ruckbeil, C, & Wick, R R. Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra. United Kingdom.
Schmitt, E, Ruckbeil, C, and Wick, R R. 1983. "Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra." United Kingdom.
@misc{etde_5295096,
title = {Long-term clinical investigation of patients with ankylosing spondylitis treated with /sup 224/Ra}
author = {Schmitt, E, Ruckbeil, C, and Wick, R R}
abstractNote = {Between 1952 and 1980 about 250 patients with ankylosing spondylitis were treated with /sup 224/Ra at the Orthopaedic University Hospital of Frankfurt/M. In 1970, 119 of them were examined and X-rayed as was another group of 40 patients in 1980. The results of those examined could be compared with a group of 40 patients treated without /sup 224/Ra. Patients with /sup 224/Ra demonstrated a long-lasting period of subjective improvement after the treatment, with reduced consumption of antirheumatoid and analgesic drugs, on the average. Blood examinations show inflammatory activities. Nevertheless, the ankylosing spondylitis proceeded. In the final stages of the disease, neither the clinical aspects nor the X-rays showed any specific changes. We observed no case of malignant bone tumor. Of the 169 examined patients, 22 had a total of 32 children after the treatment with /sup 224/Ra. Among these was a set of twins with cerebral palsy and diabetes insipidus renalis. In conclusion, /sup 224/Ra in ankylosing spondylitis is a recommended treatment without higher risk compared to the common therapy with drugs.}
journal = {Health Phys.; (United Kingdom)}
volume = {44:Sup. 1}
journal type = {AC}
place = {United Kingdom}
year = {1983}
month = {Jan}
}