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Effect of ionizing radiations on bacterial endotoxins: comparison between gamma radiations and accelerated electrons

Abstract

Determinations of the effect of radiation sterilization processing on purified endotoxins, in aqueous solution or on dried support, are reported. These observations allow us to accept gamma radiations for sterilization of parenteral devices with an estimated probability of existence of non apyrogenic items, based upon a similar definition of the usual Sterility Assurance Level (SAL = 10/sup -6/).
Publication Date:
Jan 01, 1988
Product Type:
Conference
Report Number:
CONF-870527-
Reference Number:
GBN-88-000622; EDB-88-094364
Resource Relation:
Journal Name: Radiat. Phys. Chem., Int. J. Radiat. Appl. Instrum. Part C; (United Kingdom); Journal Volume: 31:4-6; Conference: 6. international meeting on radiation processing, Ottawa, Canada, 31 May 1987
Subject:
60 APPLIED LIFE SCIENCES; ENDOTOXINS; IRRADIATION; RADIOSTERILIZATION; COMPARATIVE EVALUATIONS; ELECTRON BEAMS; GAMMA RADIATION; QUALITY ASSURANCE; RADIATION DOSES; ANTIGENS; BEAMS; DOSES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; LEPTON BEAMS; MATERIALS; PARTICLE BEAMS; RADIATIONS; STERILIZATION; TOXIC MATERIALS; TOXINS; 553006* - Agriculture & Food Technology- Other Agricultural Applications- (1987-)
OSTI ID:
5289141
Research Organizations:
Pharmacie Centrale des Hopitaux de Paris (FR)
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: RPCHD
Submitting Site:
GBN
Size:
Pages: 679-684
Announcement Date:

Citation Formats

Guyomard, S, Goury, V, and Darbord, J C. Effect of ionizing radiations on bacterial endotoxins: comparison between gamma radiations and accelerated electrons. United Kingdom: N. p., 1988. Web.
Guyomard, S, Goury, V, & Darbord, J C. Effect of ionizing radiations on bacterial endotoxins: comparison between gamma radiations and accelerated electrons. United Kingdom.
Guyomard, S, Goury, V, and Darbord, J C. 1988. "Effect of ionizing radiations on bacterial endotoxins: comparison between gamma radiations and accelerated electrons." United Kingdom.
@misc{etde_5289141,
title = {Effect of ionizing radiations on bacterial endotoxins: comparison between gamma radiations and accelerated electrons}
author = {Guyomard, S, Goury, V, and Darbord, J C}
abstractNote = {Determinations of the effect of radiation sterilization processing on purified endotoxins, in aqueous solution or on dried support, are reported. These observations allow us to accept gamma radiations for sterilization of parenteral devices with an estimated probability of existence of non apyrogenic items, based upon a similar definition of the usual Sterility Assurance Level (SAL = 10/sup -6/).}
journal = {Radiat. Phys. Chem., Int. J. Radiat. Appl. Instrum. Part C; (United Kingdom)}
volume = {31:4-6}
place = {United Kingdom}
year = {1988}
month = {Jan}
}