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Major side-effect of metrizamide. A case report

Abstract

We have presented a case showing a major side-effect following metrizamide CT cisternography. The patient was a 68-year-old woman who developed anaphylactic shock and a disturbance of consciousness 6 hours after metrizamide CT cisternography with a dose of 850 mg of iodine. In spite of vigorous therapy, she died 60 hours after the shock. Examples of anaphylactic shock by metrizamide administered intrathecally have been reported very rarely. The pathogenesis of this case was presumably due to anaphylactic shock, but other etiological factors, such as a hypothalamic dysfunction due to a disturbed glucose metabolism of the brain, may also be suspected.
Publication Date:
Oct 01, 1987
Product Type:
Journal Article
Reference Number:
JPN-88-062052; EDB-88-086493
Resource Relation:
Journal Name: CT Kenkyu; (Japan); Journal Volume: 9:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; CAT SCANNING; METRIZAMIDE; SIDE EFFECTS; ADULTS; ANAPHYLAXIS; BIOLOGICAL SHOCK; DEATH; PAIN; PATIENTS; AGE GROUPS; AMIDES; BODY; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; CONTRAST MEDIA; DIAGNOSTIC TECHNIQUES; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; SYMPTOMS; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5279370
Research Organizations:
Kumamoto Rosai Hospital (Japan)
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: CTKED
Submitting Site:
JPN
Size:
Pages: 607-610
Announcement Date:
Apr 01, 1988

Citation Formats

Sonoda, Hiroshi, Yoshida, Akimasa, Ohtsuka, Tadahiro, Takaki, Shuichi, and Matsukado, Yasuhiko. Major side-effect of metrizamide. A case report. Japan: N. p., 1987. Web.
Sonoda, Hiroshi, Yoshida, Akimasa, Ohtsuka, Tadahiro, Takaki, Shuichi, & Matsukado, Yasuhiko. Major side-effect of metrizamide. A case report. Japan.
Sonoda, Hiroshi, Yoshida, Akimasa, Ohtsuka, Tadahiro, Takaki, Shuichi, and Matsukado, Yasuhiko. 1987. "Major side-effect of metrizamide. A case report." Japan.
@misc{etde_5279370,
title = {Major side-effect of metrizamide. A case report}
author = {Sonoda, Hiroshi, Yoshida, Akimasa, Ohtsuka, Tadahiro, Takaki, Shuichi, and Matsukado, Yasuhiko}
abstractNote = {We have presented a case showing a major side-effect following metrizamide CT cisternography. The patient was a 68-year-old woman who developed anaphylactic shock and a disturbance of consciousness 6 hours after metrizamide CT cisternography with a dose of 850 mg of iodine. In spite of vigorous therapy, she died 60 hours after the shock. Examples of anaphylactic shock by metrizamide administered intrathecally have been reported very rarely. The pathogenesis of this case was presumably due to anaphylactic shock, but other etiological factors, such as a hypothalamic dysfunction due to a disturbed glucose metabolism of the brain, may also be suspected.}
journal = []
volume = {9:5}
journal type = {AC}
place = {Japan}
year = {1987}
month = {Oct}
}