Abstract
Advanced neuroblastoma, scarcely responsive to conventional therapies, can take advantage of high dose chemio-radiotherapic treatment followed by bone marrow transplant. Nineteen young patients underwent an ablative chemotherapy with high dose Vincristine and Melphalan plus Total Body Irradiation in Genoa, Italy; all of them underwent autologus bone marrow transplantation. Fourteen children were in complete remission (CR), 5 had residual disease. Thirteen are alive after a median of 7 months following transplant; 9 are in CR; 4 have disease; 1 died for toxicity; 5 for relapse. The results seem to suggest that ablative therapy should be given to patients in CR. Toxicity was not remarkable mainly as far as TBI is concerned.
Citation Formats
Dini, G, Perin, G P, Franzone, P, Corvo, R, and Scarpati, D.
Treatment of neuroblastoma. Role of total Body Irradiation.
Italy: N. p.,
1986.
Web.
Dini, G, Perin, G P, Franzone, P, Corvo, R, & Scarpati, D.
Treatment of neuroblastoma. Role of total Body Irradiation.
Italy.
Dini, G, Perin, G P, Franzone, P, Corvo, R, and Scarpati, D.
1986.
"Treatment of neuroblastoma. Role of total Body Irradiation."
Italy.
@misc{etde_5270719,
title = {Treatment of neuroblastoma. Role of total Body Irradiation}
author = {Dini, G, Perin, G P, Franzone, P, Corvo, R, and Scarpati, D}
abstractNote = {Advanced neuroblastoma, scarcely responsive to conventional therapies, can take advantage of high dose chemio-radiotherapic treatment followed by bone marrow transplant. Nineteen young patients underwent an ablative chemotherapy with high dose Vincristine and Melphalan plus Total Body Irradiation in Genoa, Italy; all of them underwent autologus bone marrow transplantation. Fourteen children were in complete remission (CR), 5 had residual disease. Thirteen are alive after a median of 7 months following transplant; 9 are in CR; 4 have disease; 1 died for toxicity; 5 for relapse. The results seem to suggest that ablative therapy should be given to patients in CR. Toxicity was not remarkable mainly as far as TBI is concerned.}
journal = []
volume = {72:12}
journal type = {AC}
place = {Italy}
year = {1986}
month = {Jan}
}
title = {Treatment of neuroblastoma. Role of total Body Irradiation}
author = {Dini, G, Perin, G P, Franzone, P, Corvo, R, and Scarpati, D}
abstractNote = {Advanced neuroblastoma, scarcely responsive to conventional therapies, can take advantage of high dose chemio-radiotherapic treatment followed by bone marrow transplant. Nineteen young patients underwent an ablative chemotherapy with high dose Vincristine and Melphalan plus Total Body Irradiation in Genoa, Italy; all of them underwent autologus bone marrow transplantation. Fourteen children were in complete remission (CR), 5 had residual disease. Thirteen are alive after a median of 7 months following transplant; 9 are in CR; 4 have disease; 1 died for toxicity; 5 for relapse. The results seem to suggest that ablative therapy should be given to patients in CR. Toxicity was not remarkable mainly as far as TBI is concerned.}
journal = []
volume = {72:12}
journal type = {AC}
place = {Italy}
year = {1986}
month = {Jan}
}