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Thyroid diagnostics

Abstract

None of the in-vitro and in-vivo methods listed permits on unambiguous diagnosis when applied alone, owing to the fact that similar or even identical findings are obtained for various individual parameters in different thyroid diseases. Further, especially the in-vitro tests are also subject to extrathyroidal effects which may mask the typical findings. The limited and varying specificity and sensitivity of the tests applied, as well as the falsification of results caused by the patients' idiosyncracies and the methodology, make it necessary to interpret and evaluate the in-vivo and in-vitro findings only if the clinical situation (anamnesis and physical examination) is known. For maximum diagnostic quality of the tests, the initial probability of the assumed type of thyroid disease must be increased (formulation of the clinical problem). The concepts of exclusion diagnosis and identification must be distinguished as well as the diagnosis of functional disturbances on the one hand and of thyroid diseases on the other. Both of this requires a qualified, specific and detailed anamnesis and examination procedure, and the clinical examination remains the obligatory basis of clinical diagnostics. In case of inexplicable discrepancies between the clinical manifestations and the findings obtained with specific methods, or between the findings obtained  More>>
Publication Date:
Mar 01, 1985
Product Type:
Journal Article
Reference Number:
FRG-84-10463; EDB-85-158758
Resource Relation:
Journal Name: Nuklearmediziner; (Germany, Federal Republic of); Journal Volume: 8:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ENDOCRINE DISEASES; DIAGNOSIS; THYROID; DIAGNOSTIC TECHNIQUES; ADENOMAS; BIOMEDICAL RADIOGRAPHY; BIOPSY; CARCINOMAS; CAT SCANNING; CYTOLOGY; OPACITY; RADIOIMMUNOASSAY; RECOMMENDATIONS; SCINTISCANNING; THYROGLOBULIN; THYROID HORMONES; THYROIDITIS; TSH; ULTRASONOGRAPHY; BIOLOGY; BODY; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DISEASES; ENDOCRINE GLANDS; GLANDS; GLOBULINS; HORMONES; ISOTOPE APPLICATIONS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; OPTICAL PROPERTIES; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PHYSICAL PROPERTIES; PITUITARY HORMONES; PROTEINS; RADIOASSAY; RADIOISOTOPE SCANNING; RADIOLOGY; TOMOGRAPHY; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550602 - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
5266738
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: NKLZD
Submitting Site:
HEDB
Size:
Pages: 67-94
Announcement Date:
Oct 01, 1985

Citation Formats

Scriba, P C, Boerner, W, Emrich, S, Gutekunst, R, Herrmann, J, Horn, K, Klett, M, Krueskemper, H L, Pfannenstiel, P, and Pickardt, C R. Thyroid diagnostics. Germany: N. p., 1985. Web.
Scriba, P C, Boerner, W, Emrich, S, Gutekunst, R, Herrmann, J, Horn, K, Klett, M, Krueskemper, H L, Pfannenstiel, P, & Pickardt, C R. Thyroid diagnostics. Germany.
Scriba, P C, Boerner, W, Emrich, S, Gutekunst, R, Herrmann, J, Horn, K, Klett, M, Krueskemper, H L, Pfannenstiel, P, and Pickardt, C R. 1985. "Thyroid diagnostics." Germany.
@misc{etde_5266738,
title = {Thyroid diagnostics}
author = {Scriba, P C, Boerner, W, Emrich, S, Gutekunst, R, Herrmann, J, Horn, K, Klett, M, Krueskemper, H L, Pfannenstiel, P, and Pickardt, C R}
abstractNote = {None of the in-vitro and in-vivo methods listed permits on unambiguous diagnosis when applied alone, owing to the fact that similar or even identical findings are obtained for various individual parameters in different thyroid diseases. Further, especially the in-vitro tests are also subject to extrathyroidal effects which may mask the typical findings. The limited and varying specificity and sensitivity of the tests applied, as well as the falsification of results caused by the patients' idiosyncracies and the methodology, make it necessary to interpret and evaluate the in-vivo and in-vitro findings only if the clinical situation (anamnesis and physical examination) is known. For maximum diagnostic quality of the tests, the initial probability of the assumed type of thyroid disease must be increased (formulation of the clinical problem). The concepts of exclusion diagnosis and identification must be distinguished as well as the diagnosis of functional disturbances on the one hand and of thyroid diseases on the other. Both of this requires a qualified, specific and detailed anamnesis and examination procedure, and the clinical examination remains the obligatory basis of clinical diagnostics. In case of inexplicable discrepancies between the clinical manifestations and the findings obtained with specific methods, or between the findings obtained with a specific method, the patient should be referred to an expert institution, or the expert institution should be consulted.}
journal = []
volume = {8:1}
journal type = {AC}
place = {Germany}
year = {1985}
month = {Mar}
}