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Normal distribution of /sup 111/In chloride on scintigram

Abstract

Indium-111-chloride (/sup 111/InCl/sub 3/) was used as a bone marrow imaging and a tumor-localizing agent in 38 patients (46 scintigrams), who were suspected of, or diagnosed as, having malignant disease, and who were irradiated for malignant disease. The regions of suspected malignant disease, of abnormally accumulated on scintigrams, and the target irradiated, were excluded to estimate the normal distribution of /sup 111/InCl/sub 3/. Scintigrams were taken 48 hrs after intravenous injection of /sup 111/InCl/sub 3/ 1 to 3 mCi. The percent and score distribution of /sup 111/InCl/sub 3/ were noted in 23 regions. As the liver showed the highest accumulation of /sup 111/In on all scintigrams, the liver was designated as 2+. Comparing with the radioactivity in the liver, other regions had similar (2+), moderately decreased (+), or severely decreased (-) accumulation on scintigram. The score is given one for 2+, 0.5 for +, 0 for -. The score and percentage distributions were: liver 100 (100%), lumbar vertebra 58.5 (100%), mediastinum 55 (100%), nasopharynx 50 (100%), testis 47.5 (59%), heart 44.5 (89%), and pelvis 43.5 (78%). Comparing this study with a previous study of /sup 111/In-BLM, score distribution in lumbar vertebra, pelvis, and skull were similar. /sup 111/In-BLM is excreted  More>>
Publication Date:
May 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-09-349869; EDB-78-033978
Resource Relation:
Journal Name: Radioisotopes (Tokyo); (Japan); Journal Volume: 26:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE MARROW; SCINTISCANNING; INDIUM 111; TISSUE DISTRIBUTION; DIAGNOSIS; HEART; INDIUM CHLORIDES; KIDNEYS; LIVER; MAN; RADIOPHARMACEUTICALS; TESTES; TIME DEPENDENCE; ANIMALS; BETA DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; CHLORIDES; CHLORINE COMPOUNDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GLANDS; GONADS; HALIDES; HALOGEN COMPOUNDS; HEMATOPOIETIC SYSTEM; INDIUM COMPOUNDS; INDIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MALE GENITALS; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PRIMATES; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TISSUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 560171 - Radiation Effects- Nuclide Kinetics & Toxicology- Man- (-1987)
OSTI ID:
5265138
Research Organizations:
Tokyo Univ., Japan
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: RAISA
Submitting Site:
INIS
Size:
Pages: 302-307
Announcement Date:
Jan 01, 1978

Citation Formats

Oyama, K, Machida, K, Hayashi, S, Watari, T, and Akaike, A. Normal distribution of /sup 111/In chloride on scintigram. Japan: N. p., 1977. Web.
Oyama, K, Machida, K, Hayashi, S, Watari, T, & Akaike, A. Normal distribution of /sup 111/In chloride on scintigram. Japan.
Oyama, K, Machida, K, Hayashi, S, Watari, T, and Akaike, A. 1977. "Normal distribution of /sup 111/In chloride on scintigram." Japan.
@misc{etde_5265138,
title = {Normal distribution of /sup 111/In chloride on scintigram}
author = {Oyama, K, Machida, K, Hayashi, S, Watari, T, and Akaike, A}
abstractNote = {Indium-111-chloride (/sup 111/InCl/sub 3/) was used as a bone marrow imaging and a tumor-localizing agent in 38 patients (46 scintigrams), who were suspected of, or diagnosed as, having malignant disease, and who were irradiated for malignant disease. The regions of suspected malignant disease, of abnormally accumulated on scintigrams, and the target irradiated, were excluded to estimate the normal distribution of /sup 111/InCl/sub 3/. Scintigrams were taken 48 hrs after intravenous injection of /sup 111/InCl/sub 3/ 1 to 3 mCi. The percent and score distribution of /sup 111/InCl/sub 3/ were noted in 23 regions. As the liver showed the highest accumulation of /sup 111/In on all scintigrams, the liver was designated as 2+. Comparing with the radioactivity in the liver, other regions had similar (2+), moderately decreased (+), or severely decreased (-) accumulation on scintigram. The score is given one for 2+, 0.5 for +, 0 for -. The score and percentage distributions were: liver 100 (100%), lumbar vertebra 58.5 (100%), mediastinum 55 (100%), nasopharynx 50 (100%), testis 47.5 (59%), heart 44.5 (89%), and pelvis 43.5 (78%). Comparing this study with a previous study of /sup 111/In-BLM, score distribution in lumbar vertebra, pelvis, and skull were similar. /sup 111/In-BLM is excreted rapidly after injection, but little /sup 111/InCl/sub 3/ is excreted. Accumulation of /sup 111/In in bone marrow depends upon the amount of /sup 111/In-transferrin in blood. High accumulation in the lumbar vertebra and pelvis shows that /sup 111/InCl/sub 3/ would be effective as a bone marrow imaging agent.}
journal = []
volume = {26:5}
journal type = {AC}
place = {Japan}
year = {1977}
month = {May}
}