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Radiation block of bone marrow cell mitoses and the effect of insulin

Journal Article:

Abstract

Insulin (0.15 - 0.2 units/kg) has been administered to white rats immediately after the exposure to 750 R, at the background of hypercorticoidism. This resulted in the inhibition of the development of the post-irradiation-stress-hyperglycemia; and the mitotic index of the bone marrow cells at the time of the mitosis block was higher than in the control irradiated rats. Insulin administration at the peak of radiation sickness during hypercorticoidism levelled hyperglycemia, stimulated the mitotic activity of cells of the bone marrow and the regeneration of the latter.
Authors:
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-09-360255; EDB-78-046761
Resource Relation:
Journal Name: Radiobiologiya; (USSR); Journal Volume: 16:1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BONE MARROW CELLS; BIOLOGICAL RADIATION EFFECTS; HYPERGLYCEMIA; RESPONSE MODIFYING FACTORS; INSULIN; BIOLOGICAL EFFECTS; BIOLOGICAL REPAIR; CORTICOSTEROIDS; INJECTION; IRRADIATION; MITOTIC INDEX; RATS; SECRETION; STIMULATION; ADRENAL HORMONES; ANIMAL CELLS; ANIMALS; BIOLOGICAL RECOVERY; CONNECTIVE TISSUE CELLS; HORMONES; HYDROXY COMPOUNDS; INTAKE; KETONES; MAMMALS; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PREGNANES; RADIATION EFFECTS; RECOVERY; REPAIR; RODENTS; SOMATIC CELLS; STEROID HORMONES; STEROIDS; VERTEBRATES; 560114* - Radiation Effects on Biochemicals- In Animals- (-1987)
OSTI ID:
5247841
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: RADOA
Submitting Site:
INIS
Size:
Pages: 54-58
Announcement Date:

Journal Article:

Citation Formats

Barkalaya, A I. Radiation block of bone marrow cell mitoses and the effect of insulin. USSR: N. p., 1976. Web.
Barkalaya, A I. Radiation block of bone marrow cell mitoses and the effect of insulin. USSR.
Barkalaya, A I. 1976. "Radiation block of bone marrow cell mitoses and the effect of insulin." USSR.
@misc{etde_5247841,
title = {Radiation block of bone marrow cell mitoses and the effect of insulin}
author = {Barkalaya, A I}
abstractNote = {Insulin (0.15 - 0.2 units/kg) has been administered to white rats immediately after the exposure to 750 R, at the background of hypercorticoidism. This resulted in the inhibition of the development of the post-irradiation-stress-hyperglycemia; and the mitotic index of the bone marrow cells at the time of the mitosis block was higher than in the control irradiated rats. Insulin administration at the peak of radiation sickness during hypercorticoidism levelled hyperglycemia, stimulated the mitotic activity of cells of the bone marrow and the regeneration of the latter.}
journal = {Radiobiologiya; (USSR)}
volume = {16:1}
journal type = {AC}
place = {USSR}
year = {1976}
month = {Jan}
}