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Natural history and outcome of antibiotic treatment of urinary tract infections in women: Hiroshima

Abstract

The present report is a review of data collected from 159 women whose positive urine cultures were detected during 4 years of a study of the late medical effects of ionizing radiation emitted during the atomic bombing of Hiroshima. Although there are always uncertainties in a retrospective analysis of data, a number of unusual features of the present series of patients provided the stimulus for undertaking the review. These features included the relatively unbiased nature of the study population, the finding of a group of patients who were untreated for sizeable intervals of time, the long follow-up after treatment and the use of quantitative bacteriologic techniques during the entire period of observation. Although the entire study population was not screened for urinary infection, the age distribution of patients with infections was similar of that found in surveys of the general population. Treatment was considered successful in about 84% of cases when evaluation was based on follow-up cultures approximately 3 months after the administration of antibiotics. When evaluation was based on 18 months or more follow-up after treatment, only about 50% of patients had negative urine cultures. These results were similar to those reported previously in hospital clinic patients. Observations on  More>>
Publication Date:
Apr 23, 1964
Product Type:
Technical Report
Report Number:
ABCC-07-64
Reference Number:
EDB-84-057942
Resource Relation:
Other Information: Portions are illegible in microfiche products
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; UROGENITAL SYSTEM DISEASES; BACTERIA; BACTERIAL DISEASES; HIROSHIMA; QUALITATIVE CHEMICAL ANALYSIS; URINARY TRACT; URINE; WOMEN; ANIMALS; ASIA; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY; BODY FLUIDS; CHEMICAL ANALYSIS; DISEASES; FEMALES; HUMAN POPULATIONS; INFECTIOUS DISEASES; JAPAN; MAMMALS; MAN; MATERIALS; MICROORGANISMS; ORGANS; POPULATIONS; PRIMATES; VERTEBRATES; WASTES; 560151* - Radiation Effects on Animals- Man; 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5240736
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
Japanese and English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008470
Availability:
NTIS, PC A02/MF A01; 1.
Submitting Site:
HEDB
Size:
Pages: 24
Announcement Date:
Apr 01, 1984

Citation Formats

Freedman, L R, Seki, Masafumi, and Phair, J P. Natural history and outcome of antibiotic treatment of urinary tract infections in women: Hiroshima. Japan: N. p., 1964. Web.
Freedman, L R, Seki, Masafumi, & Phair, J P. Natural history and outcome of antibiotic treatment of urinary tract infections in women: Hiroshima. Japan.
Freedman, L R, Seki, Masafumi, and Phair, J P. 1964. "Natural history and outcome of antibiotic treatment of urinary tract infections in women: Hiroshima." Japan.
@misc{etde_5240736,
title = {Natural history and outcome of antibiotic treatment of urinary tract infections in women: Hiroshima}
author = {Freedman, L R, Seki, Masafumi, and Phair, J P}
abstractNote = {The present report is a review of data collected from 159 women whose positive urine cultures were detected during 4 years of a study of the late medical effects of ionizing radiation emitted during the atomic bombing of Hiroshima. Although there are always uncertainties in a retrospective analysis of data, a number of unusual features of the present series of patients provided the stimulus for undertaking the review. These features included the relatively unbiased nature of the study population, the finding of a group of patients who were untreated for sizeable intervals of time, the long follow-up after treatment and the use of quantitative bacteriologic techniques during the entire period of observation. Although the entire study population was not screened for urinary infection, the age distribution of patients with infections was similar of that found in surveys of the general population. Treatment was considered successful in about 84% of cases when evaluation was based on follow-up cultures approximately 3 months after the administration of antibiotics. When evaluation was based on 18 months or more follow-up after treatment, only about 50% of patients had negative urine cultures. These results were similar to those reported previously in hospital clinic patients. Observations on a small group of untreated patients suggest that for women, the long term results of gram negative urinary tract infections is not significantly altered by a single short course of antibiotic treatment. 27 references, 7 figures, 5 tables.}
place = {Japan}
year = {1964}
month = {Apr}
}