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Case reports 1964, medicine: infantile hypertrophic pyloric stenosis in four siblings. Retinopathy and keratopathy due to chloroquine. The first instance of hemoglobin E in a Japanese family

Technical Report:

Abstract

This document contains 3 reports. In the first report four siblings are presented who had infantile pyloric stenosis unequivocally demonstrated when pyloromyotomy was performed in the early neonatal period. Their father had symptoms of stenosis as an infant but he was treated medically and it cannot be stated with certainty that he had the disease. Blood groups, determined for the four children and their parents, were not unusual. Chromosome karyotypes, obtained from peripheral blood cultures, were apparently normal. In the second report, a case study of a patient exhibiting side effects due to chloroquine used in the treatment of lupus vulgaris is presented. In the third report, in a survey for hemoglobinopathies in Nagasaki, Japan four members in two generations of a Japanese family were found to have an abnormal hemoglobin, which on detailed chemical analyses was demonstrated to be hemoglobin E. The question of prior introduction of the gene into Japan from Southeast Asia versus independent mutation is briefly discussed. 70 references, 4 figures, 5 tables.
Publication Date:
Jun 18, 1964
Product Type:
Technical Report
Report Number:
ABCC-30-64
Reference Number:
EDB-84-057627
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; EYES; PATHOLOGICAL CHANGES; HEMOGLOBIN; STOMACH; BLOOD; DRUGS; PATIENTS; SIDE EFFECTS; BIOLOGICAL MATERIALS; BODY; BODY AREAS; BODY FLUIDS; CARBOXYLIC ACIDS; DIGESTIVE SYSTEM; FACE; GASTROINTESTINAL TRACT; GLOBIN; HEAD; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; MATERIALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PIGMENTS; PORPHYRINS; PROTEINS; SENSE ORGANS; 550600* - Medicine
OSTI ID:
5217347
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
Japanese and English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008423
Availability:
NTIS, PC A03/MF A01.
Submitting Site:
HEDB
Size:
Pages: 30
Announcement Date:

Technical Report:

Citation Formats

Burmeister, R E, Hamilton, H B, Hinds, M J.A., Slavin, R E, Kamata, Nanao, Shibata, Susumu, Miller, R J, Phair, J P, Kasahara, Masayuki, and Shibata, Susumu. Case reports 1964, medicine: infantile hypertrophic pyloric stenosis in four siblings. Retinopathy and keratopathy due to chloroquine. The first instance of hemoglobin E in a Japanese family. Japan: N. p., 1964. Web.
Burmeister, R E, Hamilton, H B, Hinds, M J.A., Slavin, R E, Kamata, Nanao, Shibata, Susumu, Miller, R J, Phair, J P, Kasahara, Masayuki, & Shibata, Susumu. Case reports 1964, medicine: infantile hypertrophic pyloric stenosis in four siblings. Retinopathy and keratopathy due to chloroquine. The first instance of hemoglobin E in a Japanese family. Japan.
Burmeister, R E, Hamilton, H B, Hinds, M J.A., Slavin, R E, Kamata, Nanao, Shibata, Susumu, Miller, R J, Phair, J P, Kasahara, Masayuki, and Shibata, Susumu. 1964. "Case reports 1964, medicine: infantile hypertrophic pyloric stenosis in four siblings. Retinopathy and keratopathy due to chloroquine. The first instance of hemoglobin E in a Japanese family." Japan.
@misc{etde_5217347,
title = {Case reports 1964, medicine: infantile hypertrophic pyloric stenosis in four siblings. Retinopathy and keratopathy due to chloroquine. The first instance of hemoglobin E in a Japanese family}
author = {Burmeister, R E, Hamilton, H B, Hinds, M J.A., Slavin, R E, Kamata, Nanao, Shibata, Susumu, Miller, R J, Phair, J P, Kasahara, Masayuki, and Shibata, Susumu}
abstractNote = {This document contains 3 reports. In the first report four siblings are presented who had infantile pyloric stenosis unequivocally demonstrated when pyloromyotomy was performed in the early neonatal period. Their father had symptoms of stenosis as an infant but he was treated medically and it cannot be stated with certainty that he had the disease. Blood groups, determined for the four children and their parents, were not unusual. Chromosome karyotypes, obtained from peripheral blood cultures, were apparently normal. In the second report, a case study of a patient exhibiting side effects due to chloroquine used in the treatment of lupus vulgaris is presented. In the third report, in a survey for hemoglobinopathies in Nagasaki, Japan four members in two generations of a Japanese family were found to have an abnormal hemoglobin, which on detailed chemical analyses was demonstrated to be hemoglobin E. The question of prior introduction of the gene into Japan from Southeast Asia versus independent mutation is briefly discussed. 70 references, 4 figures, 5 tables.}
place = {Japan}
year = {1964}
month = {Jun}
}