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Serum B/sub 12/ levels in iron definiency anemia

Technical Report:

Abstract

As part of its research program to study the late effects of radiation in survivors of the atomic bombs, the Atomic Bomb Casualty Commission (ABCC) in conjunction with the Japanese National Institute of Health (JNIH), conducts biennial medical examinations on the selected population which comprises the ABCC-JHIN Adult Health Study sample. The patients herein described as Groups 1 and 2 were selected from among those examined in Nagasaki who had had a hemoglobin value of less than 11.0 g/100 ml at examination 2 years previously and who had responded to iron therapy sufficiently to justify a diagnosis of iron deficiency anemia. Almost all were women of child bearing age. The effect of iron therapy on the level of serum B/sub 12/ was investigated. Of 58 patients so studied, 46 showed some rise in post-treatment levels of B/sub 12/. This is evaluated as indicating that gastric secretion of intrinsic factor is depressed in the majority of iron deficient patients.
Publication Date:
Apr 23, 1964
Product Type:
Technical Report
Report Number:
ABCC-08-64
Reference Number:
EDB-84-057947
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; ANEMIAS; BLOOD SERUM; INTRINSIC FACTOR; IRON; NAGASAKI; THERAPY; VITAMIN B-12; ASIA; CARBOHYDRATES; DISEASES; DRUGS; ELEMENTS; HEMATINICS; HEMATOLOGIC AGENTS; HEMIC DISEASES; HUMAN POPULATIONS; JAPAN; METALS; MUCOPROTEINS; ORGANIC COMPOUNDS; POLYSACCHARIDES; POPULATIONS; PROTEINS; SACCHARIDES; SYMPTOMS; TRANSITION ELEMENTS; VITAMIN B GROUP; VITAMINS; 560151* - Radiation Effects on Animals- Man; 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5215331
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
Japanese and English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008441
Availability:
NTIS, PC A02/MF A01.
Submitting Site:
HEDB
Size:
Pages: 9
Announcement Date:
Apr 01, 1984

Technical Report:

Citation Formats

Sagan, L A, and Ohki, Keiichi. Serum B/sub 12/ levels in iron definiency anemia. Japan: N. p., 1964. Web.
Sagan, L A, & Ohki, Keiichi. Serum B/sub 12/ levels in iron definiency anemia. Japan.
Sagan, L A, and Ohki, Keiichi. 1964. "Serum B/sub 12/ levels in iron definiency anemia." Japan.
@misc{etde_5215331,
title = {Serum B/sub 12/ levels in iron definiency anemia}
author = {Sagan, L A, and Ohki, Keiichi}
abstractNote = {As part of its research program to study the late effects of radiation in survivors of the atomic bombs, the Atomic Bomb Casualty Commission (ABCC) in conjunction with the Japanese National Institute of Health (JNIH), conducts biennial medical examinations on the selected population which comprises the ABCC-JHIN Adult Health Study sample. The patients herein described as Groups 1 and 2 were selected from among those examined in Nagasaki who had had a hemoglobin value of less than 11.0 g/100 ml at examination 2 years previously and who had responded to iron therapy sufficiently to justify a diagnosis of iron deficiency anemia. Almost all were women of child bearing age. The effect of iron therapy on the level of serum B/sub 12/ was investigated. Of 58 patients so studied, 46 showed some rise in post-treatment levels of B/sub 12/. This is evaluated as indicating that gastric secretion of intrinsic factor is depressed in the majority of iron deficient patients.}
place = {Japan}
year = {1964}
month = {Apr}
}