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Electrocardiographic findings related to aging

Abstract

More than 3000 electrocardiographic tracings for the ABCC-JNIH Adult Health Study Sample were studied to detect any specific abnormalities or nonspecific age changes in relation to possible radiation effects upon the cardiovascular system. The 4 comparison groups were studied with respect to the prevalence of electrocardiographic abnormalities and an electrocardiographic aging index which was defined to evaluate physiological change with age. Statistically significant differences were observed in the following aspects: In males aged 50 to 59, the prevalence of major electrocardiographic abnormalities was highest in the group located nearest the hypocenter. This was not observed in other age groups. In females, the prevalence of QRS high voltage was highest in Group 2 but low in Group 1. This trend was consistent in all age groups. These findings were not fully accounted for by differences in blood pressure, heart size, body weight or serum cholesterol values. In the age trend curve of the electrocardiographic aging index, a difference was observed among comparison groups in both sexes. This difference in electrocardiographic aging index is mainly attributed to T/sub I/ amplitude for males and R/sub II/ amplitude and QRS axis for females. Interpretation of these findings is rather difficult since very little has  More>>
Publication Date:
Dec 12, 1962
Product Type:
Technical Report
Report Number:
ABCC-20-62
Reference Number:
EDB-84-058003
Resource Relation:
Other Information: Portions are illegible in microfiche products
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; ELECTROCARDIOGRAMS; HEART; DELAYED RADIATION EFFECTS; AGE DEPENDENCE; BLOOD CHEMISTRY; BLOOD PRESSURE; BLOOD SERUM; CARDIOVASCULAR SYSTEM; CHOLESTEROL; DATA COMPILATION; LIFE SPAN; SEX DEPENDENCE; SIZE; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DATA; DIAGRAMS; HUMAN POPULATIONS; HYDROXY COMPOUNDS; INFORMATION; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANS; POPULATIONS; RADIATION EFFECTS; STEROIDS; STEROLS; 560151* - Radiation Effects on Animals- Man; 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5214845
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
Japanese and English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008396
Availability:
NTIS, PC A03/MF A01; 1.
Submitting Site:
HEDB
Size:
Pages: 46
Announcement Date:
Apr 01, 1984

Citation Formats

Ueda, Shoichi, and Yano, Katsuhiko. Electrocardiographic findings related to aging. Japan: N. p., 1962. Web.
Ueda, Shoichi, & Yano, Katsuhiko. Electrocardiographic findings related to aging. Japan.
Ueda, Shoichi, and Yano, Katsuhiko. 1962. "Electrocardiographic findings related to aging." Japan.
@misc{etde_5214845,
title = {Electrocardiographic findings related to aging}
author = {Ueda, Shoichi, and Yano, Katsuhiko}
abstractNote = {More than 3000 electrocardiographic tracings for the ABCC-JNIH Adult Health Study Sample were studied to detect any specific abnormalities or nonspecific age changes in relation to possible radiation effects upon the cardiovascular system. The 4 comparison groups were studied with respect to the prevalence of electrocardiographic abnormalities and an electrocardiographic aging index which was defined to evaluate physiological change with age. Statistically significant differences were observed in the following aspects: In males aged 50 to 59, the prevalence of major electrocardiographic abnormalities was highest in the group located nearest the hypocenter. This was not observed in other age groups. In females, the prevalence of QRS high voltage was highest in Group 2 but low in Group 1. This trend was consistent in all age groups. These findings were not fully accounted for by differences in blood pressure, heart size, body weight or serum cholesterol values. In the age trend curve of the electrocardiographic aging index, a difference was observed among comparison groups in both sexes. This difference in electrocardiographic aging index is mainly attributed to T/sub I/ amplitude for males and R/sub II/ amplitude and QRS axis for females. Interpretation of these findings is rather difficult since very little has been known about radiation effects upon the cardiovascular system in humans. Further intensive studies are desired on the basis of the clues suggested in this report. 16 references, 3 figures, 31 tables.}
place = {Japan}
year = {1962}
month = {Dec}
}