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Clinical findings on in utero exposed microcephalic children

Technical Report:

Abstract

Since animal experiments have shown that microcephaly is induced by fetal exposure to radiation and microcephaly has been found in children of mothers exposed to x-ray therapy during pregnancy (Murphy et al), the main cause of microcephaly in children exposed in utero to the A-bomb is considered to be ionizing radiation. Wood et al reported the increased incidence of microcephaly and mental retardation in children exposed in utero at proximal distances which they felt could not be attributed to any other known variable. ABCC has recently concluded that the effect of in utero exposure is primarily due to the immediate effect of radiation upon the fetuses although in A-bomb exposure the physical injury to the mother due to the A-bomb cannot be completely ignored. Our survey likewise revealed an increase of microcephaly in children exposed early in pregnancy at less than 15 weeks at closer distances than 1500 m. Thus, we presume that A-bomb radiation increases the incidence of microcephaly. 16 references, 8 tables.
Publication Date:
Dec 24, 1966
Product Type:
Technical Report
Report Number:
ABCC-TR-28-67
Reference Number:
EDB-84-058062
Resource Relation:
Other Information: Portions are illegible in microfiche products
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; PRENATAL EXPOSURE; BRAIN; BIOLOGICAL RADIATION EFFECTS; FETUSES; MALFORMATIONS; AGE DEPENDENCE; DATA COMPILATION; HEAD; HIROSHIMA; RADIATION HAZARDS; SIZE; ASIA; BIOLOGICAL EFFECTS; BODY; BODY AREAS; CENTRAL NERVOUS SYSTEM; DATA; HAZARDS; HEALTH HAZARDS; HUMAN POPULATIONS; INFORMATION; JAPAN; NERVOUS SYSTEM; NUMERICAL DATA; ORGANS; PATHOLOGICAL CHANGES; POPULATIONS; RADIATION EFFECTS; 560151* - Radiation Effects on Animals- Man; 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man
OSTI ID:
5214333
Research Organizations:
Atomic Bomb Casualty Commission, Hiroshima (Japan)
Country of Origin:
Japan
Language:
Japanese and English
Contract Number:
AC01-76EV03081
Other Identifying Numbers:
Other: ON: DE84008118
Availability:
NTIS, PC A02/MF A01; 1.
Submitting Site:
HEDB
Size:
Pages: 24
Announcement Date:
Apr 01, 1984

Technical Report:

Citation Formats

Tabuchi, Akira, Hirai, Tsuyoshi, Nakagawa, Shigeru, Shimada, Katsunobu, and Fujito, Junro. Clinical findings on in utero exposed microcephalic children. Japan: N. p., 1966. Web.
Tabuchi, Akira, Hirai, Tsuyoshi, Nakagawa, Shigeru, Shimada, Katsunobu, & Fujito, Junro. Clinical findings on in utero exposed microcephalic children. Japan.
Tabuchi, Akira, Hirai, Tsuyoshi, Nakagawa, Shigeru, Shimada, Katsunobu, and Fujito, Junro. 1966. "Clinical findings on in utero exposed microcephalic children." Japan.
@misc{etde_5214333,
title = {Clinical findings on in utero exposed microcephalic children}
author = {Tabuchi, Akira, Hirai, Tsuyoshi, Nakagawa, Shigeru, Shimada, Katsunobu, and Fujito, Junro}
abstractNote = {Since animal experiments have shown that microcephaly is induced by fetal exposure to radiation and microcephaly has been found in children of mothers exposed to x-ray therapy during pregnancy (Murphy et al), the main cause of microcephaly in children exposed in utero to the A-bomb is considered to be ionizing radiation. Wood et al reported the increased incidence of microcephaly and mental retardation in children exposed in utero at proximal distances which they felt could not be attributed to any other known variable. ABCC has recently concluded that the effect of in utero exposure is primarily due to the immediate effect of radiation upon the fetuses although in A-bomb exposure the physical injury to the mother due to the A-bomb cannot be completely ignored. Our survey likewise revealed an increase of microcephaly in children exposed early in pregnancy at less than 15 weeks at closer distances than 1500 m. Thus, we presume that A-bomb radiation increases the incidence of microcephaly. 16 references, 8 tables.}
place = {Japan}
year = {1966}
month = {Dec}
}