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Second case of chronic granulocytic leukemia with karyotypic evolution at acute crisis, occurring in so-called Nishiyama district

Journal Article:

Abstract

The whole process of a second case of chronic granulocytic leukemia in Nishiyama district where a very small amount of radiation existed for a long time was reported together with data measured by a human counter and the results of chromosomal analysis. No significantly high K or /sup 137/Cs values were measured by a human counter immediately after the onset. Chromosomal division aberration and chromosomal aberration, which seemed to be induced by radiation, also were not observed. However, granulocytic leukemia was diagnosed after chromosomal analysis of peripheral blood revealed Ph/sup 1/ chromosomes, white cell count increased, juvenile cells appeared, and basophil cells increased. Clinical features of typical chronic granulocytic leukemia in the exposed were observed during the chronic stage (7 years). In the acute stage, abnormal clones were discovered in all 16 chromosomes analyzed. Much karyotypic evolution identical to that in persons directly exposed to the A-bomb was also observed.
Authors:
Yao, E; Tomonaga, Yu; Nishino, K; Matsunaga, M; Sadamori, N [1] 
  1. Nagasaki Univ. (Japan). School of Medicine
Publication Date:
Sep 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-11-502443; EDB-80-098593
Resource Relation:
Journal Name: Nagasaki Igakkai Zasshi; (Japan); Journal Volume: 53:3
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; CHROMOSOMAL ABERRATIONS; MYELOID LEUKEMIA; RADIOINDUCTION; CESIUM 137; CHRONIC IRRADIATION; DELAYED RADIATION EFFECTS; LOW DOSE IRRADIATION; NAGASAKI; PATIENTS; SOILS; ALKALI METAL ISOTOPES; ASIA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CESIUM ISOTOPES; CHRONIC EXPOSURE; DISEASES; HEMIC DISEASES; IRRADIATION; ISOTOPES; JAPAN; LEUKEMIA; MUTATIONS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; RADIATION EFFECTS; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES; 560151* - Radiation Effects on Animals- Man
OSTI ID:
5210833
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NAGZA
Submitting Site:
INIS
Size:
Pages: 319-324
Announcement Date:
Mar 01, 1980

Journal Article:

Citation Formats

Yao, E, Tomonaga, Yu, Nishino, K, Matsunaga, M, and Sadamori, N. Second case of chronic granulocytic leukemia with karyotypic evolution at acute crisis, occurring in so-called Nishiyama district. Japan: N. p., 1978. Web.
Yao, E, Tomonaga, Yu, Nishino, K, Matsunaga, M, & Sadamori, N. Second case of chronic granulocytic leukemia with karyotypic evolution at acute crisis, occurring in so-called Nishiyama district. Japan.
Yao, E, Tomonaga, Yu, Nishino, K, Matsunaga, M, and Sadamori, N. 1978. "Second case of chronic granulocytic leukemia with karyotypic evolution at acute crisis, occurring in so-called Nishiyama district." Japan.
@misc{etde_5210833,
title = {Second case of chronic granulocytic leukemia with karyotypic evolution at acute crisis, occurring in so-called Nishiyama district}
author = {Yao, E, Tomonaga, Yu, Nishino, K, Matsunaga, M, and Sadamori, N}
abstractNote = {The whole process of a second case of chronic granulocytic leukemia in Nishiyama district where a very small amount of radiation existed for a long time was reported together with data measured by a human counter and the results of chromosomal analysis. No significantly high K or /sup 137/Cs values were measured by a human counter immediately after the onset. Chromosomal division aberration and chromosomal aberration, which seemed to be induced by radiation, also were not observed. However, granulocytic leukemia was diagnosed after chromosomal analysis of peripheral blood revealed Ph/sup 1/ chromosomes, white cell count increased, juvenile cells appeared, and basophil cells increased. Clinical features of typical chronic granulocytic leukemia in the exposed were observed during the chronic stage (7 years). In the acute stage, abnormal clones were discovered in all 16 chromosomes analyzed. Much karyotypic evolution identical to that in persons directly exposed to the A-bomb was also observed.}
journal = {Nagasaki Igakkai Zasshi; (Japan)}
volume = {53:3}
journal type = {AC}
place = {Japan}
year = {1978}
month = {Sep}
}