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Intrathecal application of /sup 198/Au colloid in acute leukemia and non-Hodgkin's lymphoma in chilhood. 2. Metaphylaxis of meningosis neoplastica

Journal Article:

Abstract

7 children suffering from acute lymphatic leukemia (ALL) and non-Hodgkin's lymphoma, resp., were injected intrathecally with /sup 198/Au colloid for metaphylaxis. The children had been cured of 8 relapses of miningosis and received irregularly intrathecal injections of methotrexate for cerebral maintenance therapy. The median cerebral period of remission was 52 weeks. 1 child suffering from ALL had been free from meningosis relapses for 128 weeks. Continuous cytostatic therapy is necessary for methaphylaxis. However, despite of the good results presented, /sup 198/Au colloid can not be recommended for long-term therapy because radiation injuries are to be expected.
Authors:
Metz, O; Unverricht, A; Stoll, W [1] 
  1. Friedrich-Schiller-Universitaet, Jena (German Democratic Republic)
Publication Date:
Aug 01, 1979
Product Type:
Journal Article
Reference Number:
AIX-11-502697; EDB-80-098652
Resource Relation:
Journal Name: Dtsch. Gesundheitswes.; (German Democratic Republic); Journal Volume: 34:35
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; DELAYED RADIATION EFFECTS; METASTASES; RADIOTHERAPY; SIDE EFFECTS; CHILDREN; GOLD 198; HODGKINS DISEASE; INTERNAL IRRADIATION; LEUKEMIA; MENINGES; METHOTREXATE; NUCLEAR MEDICINE; RADIATION DOSES; RADIOCOLLOIDS; ANIMALS; ANTIMETABOLITES; ANTIMITOTIC DRUGS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; COLLOIDS; DAYS LIVING RADIOISOTOPES; DISEASES; DISPERSIONS; DOSES; DRUGS; GOLD ISOTOPES; HEAVY NUCLEI; HEMIC DISEASES; IRRADIATION; ISOTOPES; LYMPHOMAS; MAMMALS; MAN; MEDICINE; MEMBRANES; NEOPLASMS; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANS; PRIMATES; RADIATION EFFECTS; RADIOISOTOPES; RADIOLOGY; THERAPY; VERTEBRATES; 560161* - Radionuclide Effects, Kinetics, & Toxicology- Man; 550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)
OSTI ID:
5210375
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: DEGEA
Submitting Site:
INIS
Size:
Pages: 1676-1679
Announcement Date:

Journal Article:

Citation Formats

Metz, O, Unverricht, A, and Stoll, W. Intrathecal application of /sup 198/Au colloid in acute leukemia and non-Hodgkin's lymphoma in chilhood. 2. Metaphylaxis of meningosis neoplastica. Germany: N. p., 1979. Web.
Metz, O, Unverricht, A, & Stoll, W. Intrathecal application of /sup 198/Au colloid in acute leukemia and non-Hodgkin's lymphoma in chilhood. 2. Metaphylaxis of meningosis neoplastica. Germany.
Metz, O, Unverricht, A, and Stoll, W. 1979. "Intrathecal application of /sup 198/Au colloid in acute leukemia and non-Hodgkin's lymphoma in chilhood. 2. Metaphylaxis of meningosis neoplastica." Germany.
@misc{etde_5210375,
title = {Intrathecal application of /sup 198/Au colloid in acute leukemia and non-Hodgkin's lymphoma in chilhood. 2. Metaphylaxis of meningosis neoplastica}
author = {Metz, O, Unverricht, A, and Stoll, W}
abstractNote = {7 children suffering from acute lymphatic leukemia (ALL) and non-Hodgkin's lymphoma, resp., were injected intrathecally with /sup 198/Au colloid for metaphylaxis. The children had been cured of 8 relapses of miningosis and received irregularly intrathecal injections of methotrexate for cerebral maintenance therapy. The median cerebral period of remission was 52 weeks. 1 child suffering from ALL had been free from meningosis relapses for 128 weeks. Continuous cytostatic therapy is necessary for methaphylaxis. However, despite of the good results presented, /sup 198/Au colloid can not be recommended for long-term therapy because radiation injuries are to be expected.}
journal = {Dtsch. Gesundheitswes.; (German Democratic Republic)}
volume = {34:35}
journal type = {AC}
place = {Germany}
year = {1979}
month = {Aug}
}