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Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA

Journal Article:

Abstract

Methods and clinical indications of divided renal clearance determination using /sup 131/I-hippuran are presented and their value as a diagnostic tool in urology is shown by two case reports. For quantitative assessment of renal function we prefer the whole body clearance (with partial shielding of kidneys and bladder) which obviates the necessity of the theoretical assumption of compartmental distribution of radiopharmaceuticals. Using simplified clearance techniques only based on analysis of plasma disappearance curves (slope clearance one- and two-compartment model), clinically useful results are also obtainable, especially in follow up studies. The evaluation of tubular and glomerular kidney function by simultaneous application of /sup 131/I-hippuran and sup(99m)Tc-DTPA is suitable for estimation of filtration fraction in patients with urological and nephrological diseases. Even with regard to therapy and follow up studies of urinary tract tuberculosis, remarkable dignostic informations may be achieved.
Authors:
Heidenreich, P; Hoer, G [1] 
  1. Technische Univ. Muenchen (Germany, F.R.). Nuklearmedizinische Klinik und Poliklinik
Publication Date:
Jan 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-09-352048; EDB-78-051631
Resource Relation:
Journal Name: Fortschr. Med.; (Germany, Federal Republic of); Journal Volume: 94:30
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; IODINE 131; RENAL CLEARANCE; KIDNEYS; BIOLOGICAL FUNCTIONS; RADIOPHARMACEUTICALS; DIAGNOSTIC TECHNIQUES; TECHNETIUM 99; UROGENITAL SYSTEM DISEASES; DIAGNOSIS; DISTRIBUTION; DTPA; HIPPURAN; ISOMERIC NUCLEI; PATIENTS; TUBERCULOSIS; URINARY TRACT; WHOLE-BODY COUNTERS; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CHELATING AGENTS; CLEARANCE; CONTRAST MEDIA; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; EXCRETION; HOURS LIVING RADIOISOTOPES; INFECTIOUS DISEASES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MEASURING INSTRUMENTS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION DETECTORS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
5186806
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: FMDZA
Submitting Site:
INIS
Size:
Pages: 1705-1712
Announcement Date:
Jan 01, 1978

Journal Article:

Citation Formats

Heidenreich, P, and Hoer, G. Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA. Germany: N. p., 1976. Web.
Heidenreich, P, & Hoer, G. Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA. Germany.
Heidenreich, P, and Hoer, G. 1976. "Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA." Germany.
@misc{etde_5186806,
title = {Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA}
author = {Heidenreich, P, and Hoer, G}
abstractNote = {Methods and clinical indications of divided renal clearance determination using /sup 131/I-hippuran are presented and their value as a diagnostic tool in urology is shown by two case reports. For quantitative assessment of renal function we prefer the whole body clearance (with partial shielding of kidneys and bladder) which obviates the necessity of the theoretical assumption of compartmental distribution of radiopharmaceuticals. Using simplified clearance techniques only based on analysis of plasma disappearance curves (slope clearance one- and two-compartment model), clinically useful results are also obtainable, especially in follow up studies. The evaluation of tubular and glomerular kidney function by simultaneous application of /sup 131/I-hippuran and sup(99m)Tc-DTPA is suitable for estimation of filtration fraction in patients with urological and nephrological diseases. Even with regard to therapy and follow up studies of urinary tract tuberculosis, remarkable dignostic informations may be achieved.}
journal = {Fortschr. Med.; (Germany, Federal Republic of)}
volume = {94:30}
journal type = {AC}
place = {Germany}
year = {1976}
month = {Jan}
}